Sorbent Manifold Bypass Control for Home Dialysis Priming

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Solution Overview

Problem

Conventional dialysis systems lack effective control over fluid direction during priming and treatment modes, leading to inefficiencies, complexity, and increased maintenance requirements, making them unsuitable for home use and prone to issues like fluid waste and sorbent cartridge ammonia breakthrough.

Innovation Solution

A sorbent manifold with integrated valves and sensors that actively control fluid flow based on sensor measurements, allowing bypass or passage through a sorbent cartridge to manage ammonia breakthrough and pressure, reducing complexity and enhancing portability.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Ease of operation

If conventional tubing systems are used to connect fluid pathways, then the system can be assembled, but the device becomes too complicated to service in home settings and requires professional training

Engineering Contradiction:
Improveease of servicingVSAvoidtubing complexity
Core Design Contradiction:
Ease of operationVSDevice complexity

Solution Approach 1:

The patent merges multiple separate tubing connections and fluid pathways into a single integrated manifold component. The manifold consolidates what would otherwise require multiple separate tubing segments, connectors, and junctions into one pre-assembled unit with multiple ports and internal passageways, dramatically reducing assembly complexity and servicing difficulty for home use

Inventive Principle:
Principle #5Merging (Combining)

Solution Approach 2:

The manifold serves multiple functions simultaneously: it acts as a fluid distribution hub, a structural support element, a connection point for multiple components (sorbent cartridge, sensors, valves), and a pathway integrator. This multi-functionality replaces what would otherwise require several separate components and extensive tubing networks

Inventive Principle:
Principle #6Universality (Multi-functionality)

2Adaptability or versatility

If complex tubing systems are used to form multiple fluid pathways, then fluid can be directed through various components, but the volume occupied increases and compartment spaces become larger than necessary

Engineering Contradiction:
Improvefluid pathway flexibilityVSAvoiddevice volume
Core Design Contradiction:
Adaptability or versatilityVSVolume of moving object

Solution Approach 1:

The manifold combines multiple fluid pathways that would otherwise require separate tubing running through the device into integrated internal channels within a single compact component. This consolidation maintains the ability to direct fluid through multiple pathways while occupying minimal space

Inventive Principle:
Principle #5Merging (Combining)

3Reliability

If conventional tubing systems are used, then fluid can flow through the system, but the snaking tubes are prone to kinking, leakage, or damage

Engineering Contradiction:
Improvefluid pathway reliabilityVSAvoidtubing arrangement
Core Design Contradiction:
ReliabilityVSDevice complexity

Solution Approach 1:

The manifold replaces multiple separate tubing segments with integrated internal passageways formed as a single rigid structure. This eliminates the joints, connectors, and flexible tubing sections that are prone to kinking, leakage, or damage, while maintaining reliable fluid flow paths

Inventive Principle:
Principle #5Merging (Combining)

Solution Approach 2:

The manifold uses smooth, curved internal channels instead of sharp angles or rigid straight lines, allowing fluid to flow smoothly around bends without creating stress concentration points or dead zones where contamination could occur

Inventive Principle:
Principle #14Spheroidality (Curvature)

4Productivity

If conventional dialysis systems without active fluid control are used, then the system can operate, but fluid is wasted and extra time is required to complete priming operations

Engineering Contradiction:
Improvepriming efficiencyVSAvoidfluid waste
Core Design Contradiction:
ProductivityVSLoss of substance

Solution Approach 1:

The manifold is pre-configured with dedicated priming pathways and valve arrangements that allow priming fluid to be directed exactly where needed without having to flush entire circuits. The integrated design enables selective activation of only the necessary fluid pathways during priming, preventing waste and reducing time

Inventive Principle:
Principle #10Preliminary action

Solution Approach 2:

The system incorporates sensors that monitor fluid flow, pressure, and priming status, providing feedback to control valves that automatically adjust fluid direction and flow rates. This closed-loop control prevents over-priming, detects when priming is complete, and eliminates fluid waste by stopping flow at the appropriate moment

Inventive Principle:
Principle #23Feedback

5Object-affected harmful factors

If conventional systems without selective bypass control are used, then fluid can flow through the system, but dialysate cannot be directed away from the sorbent cartridge under harmful circumstances

Engineering Contradiction:
Improveammonia breakthrough protectionVSAvoidfluid control system
Core Design Contradiction:
Object-affected harmful factorsVSDevice complexity

Solution Approach 1:

Sensors monitor ammonia levels, pressure, and fluid characteristics in real-time, providing feedback to control valves that automatically bypass the sorbent cartridge when harmful conditions are detected. This active monitoring and response system protects against ammonia breakthrough while maintaining a relatively simple overall device structure

Inventive Principle:
Principle #23Feedback

Solution Approach 2:

The manifold acts as an intermediary control element between the pump, sorbent cartridge, and dialysate reservoir, using integrated valves to mediate fluid flow direction. This centralized control point enables selective bypass protection without requiring complex distributed control throughout the entire system

Inventive Principle:
Principle #24Intermediary (Mediator)

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The sorbent manifold provides efficient fluid control, reducing waste, simplifying maintenance, and enabling compact, portable dialysis systems suitable for home use, while minimizing sorbent cartridge stress and fluid loss.

Implementation Method 1

A sorbent dialysis system uses a sorbent cartridge containing one or more sorbent materials to remove impurities from dialysate in the dialysis system

Methodology Applied
Scientific EffectAdsorption: Adsorption

Data Source

PatentUS20250375558A1Sorbent manifold for a dialysis system
Publication Date: 2025.12.11 MOZARC MEDICAL US LLC
  • US20250375558A1 patent drawing
  • US20250375558A1 patent drawing
  • US20250375558A1 patent drawing

AI summary

The present invention relates to a sorbent manifold and related systems and methods having a plurality of passageways fluidly connectable to one or more valves and one or more sensors and components for use in a sorbent dialysis system. The sorbent manifold can control the one or more valves to direct fluid to either pass through a sorbent cartridge or bypass the sorbent cartridge based on measurements obtained from sensors.