Sorbent Recharging System Using Patient Data
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Solution Overview
Problem
Current methods for recharging zirconium phosphate and zirconium oxide in sorbent modules are inefficient, leading to excessive chemical usage and waste, as they do not precisely match the recharge process with actual cartridge needs and usage, resulting in higher volumes of chemicals being used than necessary, and fail to customize dialysate bicarbonate levels effectively.
Innovation Solution
A method and system for recharging zirconium phosphate and zirconium oxide sorbent modules by pumping specific volumes and concentrations of recharge solutions based on patient and dialysis session parameters, including pre-dialysis levels, dialysis time, and other factors, to achieve a desired effluent pH and optimize chemical usage.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Reliability
If conventional recharging methods use excess recharge solutions to ensure complete recharging, then reliability of sorbent recharging is improved, but loss of substance increases due to excessive chemical usage
Solution Approach 1:
The system changes the parameters of the recharge process by using patient-specific data (weight, surface area, dialysis duration) to calculate and adjust the volume and concentration of recharge solutions. This allows the recharging process to be optimized for each patient rather than using fixed excessive amounts, thereby maintaining complete recharging reliability while reducing chemical waste.
Solution Approach 2:
The system implements feedback by using actual patient data and treatment parameters to determine the precise recharge solution requirements. The calculated recharge volumes are based on measured patient characteristics and treatment duration, creating a closed-loop system that adjusts chemical usage to match actual needs, thus preventing both over-recharging and chemical waste.
2Ease of operation
If conventional methods use fixed volumes of recharge solutions, then ease of operation is improved, but manufacturing precision deteriorates in matching actual cartridge needs
Solution Approach 1:
The system transitions from static fixed-volume recharging to a dynamic approach where recharge solution volumes are calculated based on patient-specific parameters including weight, surface area, and dialysis duration. This dynamic calculation ensures precise matching of recharge needs while maintaining operational simplicity through automated computation and standardized protocols.
3Object-generated harmful factors
If zirconium phosphate effluent pH is lowered to remove excess CO2, then harmful factors are reduced, but object-generated harmful factors increase due to potential hemolysis and bubble formation
Solution Approach 1:
The system optimizes the zirconium phosphate effluent pH to a specific range (5.5-6.5) that balances CO2 removal effectiveness with patient safety. By maintaining pH within this optimized range, the system achieves sufficient CO2 elimination while preventing the harmful effects of overly acidic conditions, including hemolysis and bubble formation.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
This approach allows for precise and efficient recharging of sorbent modules, reducing chemical usage and waste, while customizing dialysate bicarbonate levels to meet individual patient needs, thereby minimizing costs and improving treatment efficacy.
Implementation Method 1
Zirconium phosphate is used in sorbent dialysis to remove waste and unwanted solutes including ammonium, potassium, calcium, and magnesium ions from dialysate
Implementation Method 2
Zirconium oxide can be used to remove phosphate ions from dialysate
Implementation Method 3
recharging a sorbent material within a sorbent module by pumping one or more recharge solutions through the sorbent module
Data Source
AI summary
The invention relates to devices, systems, and methods for recharging zirconium phosphate and/or zirconium oxide in reusable sorbent modules. The devices, systems, and methods provide for precision recharging of the zirconium phosphate and/or zirconium oxide to avoid the need of excess recharge solutions. The devices systems and methods also provide for calculation of the volumes of recharge solution needed for fully recharging the zirconium phosphate and zirconium oxide modules.