Soybean Variety 01046252 Marker-Assisted Breeding

Resolve Bottlenecks,
Find Innovative Solutions
Generate Solutions

Solution Overview

Problem

Current soybean breeding methods face challenges in developing stable, high-yielding varieties with desirable traits such as disease resistance, drought tolerance, and improved nutritional quality, as they rely on conventional breeding techniques that are time-consuming and unpredictable, leading to genetic variability and environmental dependence.

Innovation Solution

The development of the soybean variety 01046252, which incorporates a single locus conversion through genetic transformation, conferring traits like herbicide resistance, disease resistance, and improved nutritional quality, and can be propagated using methods like backcrossing and marker-assisted selection to maintain desired morphological and physiological characteristics.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Adaptability or versatility

If conventional breeding techniques are used, then genetic diversity is maintained, but breeding time and unpredictability increase

Engineering Contradiction:
Improvegenetic diversityVSAvoidbreeding time
Core Design Contradiction:
Adaptability or versatilityVSLoss of time

Solution Approach 1:

The patent applies parameter changes by utilizing molecular markers to detect and select for specific genetic traits at the DNA level, transforming the breeding process from phenotypic selection to genotypic selection. This allows breeders to identify desired traits (such as disease resistance or yield components) directly through marker-assisted selection, dramatically reducing the time required for breeding cycles while maintaining genetic diversity through precise control over which genetic variants are selected.

Inventive Principle:
Principle #35Parameter changes

2Adaptability or versatility

If conventional breeding techniques are used, then natural genetic variation is preserved, but trait prediction accuracy decreases

Engineering Contradiction:
Improvenatural genetic variationVSAvoidtrait prediction accuracy
Core Design Contradiction:
Adaptability or versatilityVSMeasurement precision

Solution Approach 1:

The patent replaces the mechanical/phenotypic observation system with a molecular detection system. Instead of visually assessing plant traits or waiting for phenotypic expression, the invention uses molecular markers to directly detect the presence of desired genetic traits at the DNA level. This substitution provides precise prediction of trait inheritance and expression, allowing breeders to accurately predict which plants will exhibit desired characteristics before actual phenotypic expression occurs.

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

3Manufacturing precision

If genetic transformation is used, then desired traits are precisely introduced, but breeding program complexity increases

Engineering Contradiction:
Improvetrait introduction precisionVSAvoidbreeding program complexity
Core Design Contradiction:
Manufacturing precisionVSDevice complexity

Solution Approach 1:

The patent uses molecular markers as intermediaries between the genetic transformation process and the breeding selection process. Rather than directly tracking complex transgenic events or relying on phenotypic expression, the invention introduces detectable molecular markers that serve as proxies for the desired traits. These markers act as intermediaries that simplify the monitoring and selection process, allowing breeders to precisely track the introduction and inheritance of transformed traits without managing the full complexity of the transformation events themselves.

Inventive Principle:
Principle #24Intermediary (Mediator)

Data Source

PatentUS9480223B2Soybean variety 01046252
Publication Date: 2016.11.01 MONSANTO TECHNOLOGY LLC

AI summary

The invention relates to the soybean variety designated 01046252. Provided by the invention are the seeds, plants and derivatives of the soybean variety 01046252. Also provided by the invention are tissue cultures of the soybean variety 01046252 and the plants regenerated therefrom. Still further provided by the invention are methods for producing soybean plants by crossing the soybean variety 01046252 with itself or another soybean variety and plants produced by such methods.