Soybean 01072239 Single-Locus Conversion for Trait Stability
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Solution Overview
Problem
Current soybean breeding methods face challenges in developing stable, high-yielding varieties with improved traits such as disease resistance, drought tolerance, and herbicide resistance, which are difficult to combine effectively using conventional breeding techniques.
Innovation Solution
The development of the soybean variety 01072239, which includes a single locus conversion that can confer traits like herbicide resistance, disease resistance, and improved nutritional quality through genetic modification using techniques like genome editing with engineered nucleases, and the use of specific transgenic genes such as MON89788 and MON87708, allowing for the introduction of desired traits while maintaining the morphological and physiological characteristics of the soybean variety.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Adaptability or versatility
If conventional breeding techniques are used to combine multiple traits (disease resistance, drought tolerance, herbicide resistance), then the complexity of breeding programs increases and the time required to develop stable varieties extends, but the ability to effectively combine all desired traits is limited
Solution Approach 1:
The patent applies parameter changes by using genome editing technology to directly modify specific genetic loci, transforming the breeding approach from complex multi-generational crossing to precise single-locus conversion. This allows efficient combination of multiple traits (herbicide resistance, disease resistance, nutritional quality) by modifying individual genes rather than managing complex breeding programs across multiple generations.
Solution Approach 2:
The patent replaces the mechanical breeding process (crossing, selection, and stabilization across multiple generations) with a more precise genetic engineering approach. Instead of relying on traditional mechanical breeding techniques that require extensive field testing and selection over several years, the invention uses targeted genome editing to directly introduce desired traits, significantly reducing program complexity and development time.
2Reliability
If conventional breeding methods are used to develop new varieties, then the process requires multiple generations of testing and selection, but the time to market and the stability of trait expression are compromised
Solution Approach 1:
The patent applies preliminary action by performing the genetic modification in advance through single-locus conversion, rather than relying on multiple generations of selection and testing. The desired traits are introduced directly into the genome at a specific locus, and the variety is then stabilized through a single backcross generation, dramatically reducing the time required compared to conventional multi-generational breeding while ensuring reliable trait expression.
3Adaptability or versatility
If multiple traits are introduced through traditional breeding, then the genetic background becomes more complex and harder to stabilize, but maintaining morphological and physiological characteristics of the original variety becomes more difficult
Solution Approach 1:
The patent applies local quality by introducing trait diversity through single-locus conversion, modifying only specific genetic locations while preserving the rest of the genetic background. This allows the incorporation of multiple desirable traits (herbicide resistance, disease resistance, nutritional quality) at different loci without disrupting the overall genetic stability and morphological characteristics of the original variety, maintaining local improvements while preserving global consistency.
Data Source
AI summary
The invention relates to the soybean variety designated 01072239. Provided by the invention are the seeds, plants and derivatives of the soybean variety 01072239. Also provided by the invention are tissue cultures of the soybean variety 01072239 and the plants regenerated therefrom. Still further provided by the invention are methods for producing soybean plants by crossing the soybean variety 01072239 with itself or another soybean variety and plants produced by such methods.