Soybean Variety 01077438 Multi-Trait Breeding

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Solution Overview

Problem

Current soybean breeding methods face challenges in developing stable, high-yielding varieties with improved traits such as disease resistance, drought tolerance, and enhanced nutritional quality, which are difficult to predict and require extensive research efforts due to the complexity of genetic combinations and environmental factors.

Innovation Solution

The development of the soybean variety 01077438, which includes specific genetic modifications and locus conversions for traits like herbicide resistance, disease resistance, and modified fatty acid composition, achieved through genetic transformation and backcrossing techniques, allowing for the introduction of desired traits while maintaining the original variety's morphological and physiological characteristics.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Adaptability or versatility

If traditional breeding methods are used to develop soybean varieties with improved traits, then genetic diversity and trait combinations can be explored, but the process becomes time-consuming and unpredictable due to complexity of genetic combinations and environmental factors

Engineering Contradiction:
Improvetrait combination capabilityVSAvoidbreeding development time
Core Design Contradiction:
Adaptability or versatilityVSLoss of time

Solution Approach 1:

The patent applies preliminary action by pre-modifying specific genetic loci in parental lines before crossing. The parental soybean lines are prepared in advance with known genetic modifications (such as herbicide resistance genes or fatty acid modification genes) already integrated at specific loci. This preliminary genetic preparation allows the breeding process to proceed more efficiently, as the desired traits are already present in the parental generation rather than requiring extensive screening and selection across multiple generations, thereby reducing the overall breeding development time while maintaining genetic diversity.

Inventive Principle:
Principle #10Preliminary action

2Reliability

If multiple traits are combined in a single soybean variety, then agronomic performance and nutritional quality are improved, but the genetic complexity and difficulty of achieving stable inheritance increase

Engineering Contradiction:
Improveagronomic performance stabilityVSAvoidgenetic modification complexity
Core Design Contradiction:
ReliabilityVSDevice complexity

Solution Approach 1:

The patent applies segmentation by dividing the multi-trait improvement process into separate modular genetic loci. Each desired trait (herbicide resistance, fatty acid composition, disease resistance) is introduced at a distinct genetic locus through independent genetic modification events. This modular approach allows each trait to be developed and stabilized independently before combination, reducing the overall genetic complexity management burden. The segmented loci can then be combined through controlled crossing and backcrossing, with each locus inheriting independently, thereby improving reliability of agronomic performance while managing genetic modification complexity through systematic organization.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The patent applies local quality by making specific, targeted genetic modifications at particular loci rather than genome-wide changes. Each genetic locus is modified to confer a specific function (e.g., a particular enzyme gene modified to change fatty acid composition, or a specific resistance gene inserted for disease resistance). This localized approach allows precise control over each trait's expression and inheritance patterns, enabling stable multi-trait varieties without overwhelming genetic complexity. The local modifications can be tracked and selected for independently during breeding, facilitating reliable trait combination.

Inventive Principle:
Principle #3Local quality

3Productivity

If genetic transformation techniques are used to introduce specific traits, then breeding efficiency and trait precision are improved, but the device complexity and technical requirements increase

Engineering Contradiction:
Improvebreeding efficiencyVSAvoidtransformation system complexity
Core Design Contradiction:
ProductivityVSDevice complexity

Solution Approach 1:

The patent applies the intermediary principle by using vector systems and selectable markers as mediators in the genetic transformation process. The transformation vectors serve as intermediaries to deliver desired genes into the soybean genome, with selectable marker genes acting as intermediaries to identify and select successfully transformed cells. This intermediary approach simplifies the overall transformation system by providing standardized, well-characterized tools that can be applied across different transformation methods (Agrobacterium-mediated, biolistics, etc.), thereby improving breeding efficiency without requiring de novo development of complex transformation systems for each trait.

Inventive Principle:
Principle #24Intermediary (Mediator)

Data Source

PatentUS10743493B2Soybean variety 01077438
Publication Date: 2020.08.18 MONSANTO TECHNOLOGY LLC

AI summary

The invention relates to the soybean variety designated 01077438. Provided by the invention are the seeds, plants and derivatives of the soybean variety 01077438. Also provided by the invention are tissue cultures of the soybean variety 01077438 and the plants regenerated therefrom. Still further provided by the invention are methods for producing soybean plants by crossing the soybean variety 01077438 with itself or another soybean variety and plants produced by such methods.