Soybean Variety 01094730 Breeding Stability via CRISPR and Markers

Resolve Bottlenecks,
Find Innovative Solutions
Generate Solutions

Solution Overview

Problem

Current soybean breeding methods face challenges in developing stable, high-yielding varieties with improved traits such as disease resistance, drought tolerance, and herbicide resistance, which are difficult to predict and require extensive research and time due to the unpredictability of genetic combinations in conventional breeding.

Innovation Solution

The development of the soybean variety 01094730, which includes specific genetic modifications and locus conversions for traits like herbicide resistance, disease resistance, and improved agronomic characteristics through backcrossing and genetic transformation, using techniques like CRISPR-Cas systems and Agrobacterium-mediated transformation.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Adaptability or versatility

If conventional breeding methods are used to develop soybean varieties with improved traits, then genetic diversity and trait combinations can be explored, but the process requires extensive research and time due to unpredictability of genetic combinations

Engineering Contradiction:
Improvetrait combination diversityVSAvoidbreeding development time
Core Design Contradiction:
Adaptability or versatilityVSLoss of time

Solution Approach 1:

The patent applies preliminary action by pre-selecting parental lines with desired traits (herbicide resistance, disease resistance, yield characteristics) before crossing. The breeding program systematically evaluates parental germplasm and plans crosses based on predetermined breeding objectives, reducing the time needed to develop varieties with specific trait combinations.

Inventive Principle:
Principle #10Preliminary action

Solution Approach 2:

The patent employs feedback mechanisms through systematic evaluation of breeding progeny for desired traits. Performance data from field trials and genetic analysis feed back into the breeding program to guide selection decisions and improve subsequent crosses, accelerating the development of varieties with predictable trait expressions.

Inventive Principle:
Principle #23Feedback

2Manufacturing precision

If backcrossing and genetic transformation techniques are used to introduce specific traits, then precision in trait introduction is improved, but device complexity and breeding process complexity increase

Engineering Contradiction:
Improvetrait introduction precisionVSAvoidbreeding process complexity
Core Design Contradiction:
Manufacturing precisionVSDevice complexity

Solution Approach 1:

The patent applies segmentation by breaking down the complex breeding process into distinct stages: parental selection, controlled crossing, backcrossing generations, and trait evaluation. Each stage focuses on specific objectives, making the overall complex process more manageable and systematic while maintaining precision in trait introduction.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The patent uses molecular markers as intermediaries to track and select for desired traits during backcrossing. These markers serve as proxies for complex genetic traits, enabling precise selection without directly observing all genetic combinations, thus reducing process complexity while maintaining precision.

Inventive Principle:
Principle #24Intermediary (Mediator)

3Reliability

If extensive breeding research is conducted to ensure variety stability and uniformity, then variety reliability is improved, but productivity and breeding efficiency decrease

Engineering Contradiction:
Improvevariety stabilityVSAvoidbreeding efficiency
Core Design Contradiction:
ReliabilityVSProductivity

Solution Approach 1:

The patent replaces traditional mechanical phenotypic evaluation with molecular marker-based genotypic analysis. This substitution allows for more efficient and accurate assessment of genetic stability and uniformity, reducing the time and resources needed for extensive field trials while maintaining or improving variety reliability.

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

Data Source

PatentUS20240164291A1Soybean variety 01094730
Publication Date: 2024.05.23 MONSANTO TECHNOLOGY LLC

AI summary

The invention relates to the soybean variety designated 01094730. Provided by the invention are the seeds, plants and derivatives of the soybean variety 01094730. Also provided by the invention are tissue cultures of the soybean variety 01094730 and the plants regenerated therefrom. Still further provided by the invention are methods for producing soybean plants by crossing the soybean variety 01094730 with itself or another soybean variety and plants produced by such methods.