Soybean Variety 01106137 for Precise Multi-Trait Breeding
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Solution Overview
Problem
Existing soybean varieties lack improved combinations of traits such as higher seed yield, disease and insect resistance, drought and heat tolerance, better agronomic quality, and enhanced compositional traits, which are essential for maximizing grain production and meeting food demands.
Innovation Solution
Development of the novel soybean variety 01106137, which incorporates genetic modifications and single locus conversions for herbicide resistance, disease resistance, and improved nutritional quality, achieved through methods like genome editing using engineered nucleases, and traditional breeding techniques.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Manufacturing precision
If traditional breeding techniques are used to develop soybean varieties, then genetic diversity is maintained, but the precision and speed of introducing specific traits is limited
Solution Approach 1:
The patent replaces traditional mechanical breeding methods (crossing, selection, and recombination) with molecular-level genetic engineering techniques. Specifically, engineered nucleases (such as CRISPR-Cas9, TALENs, or zinc finger nucleases) are used to directly edit the genome at specific loci, enabling precise introduction of desired traits without relying on random genetic recombination. This substitution of mechanical breeding with molecular editing achieves both higher precision and faster development time.
2Productivity
If multiple traits are combined in a single variety to meet program goals, then agronomic performance is improved, but the complexity of breeding programs increases
Solution Approach 1:
The patent merges multiple desirable traits (herbicide resistance, disease resistance, yield improvement, nutritional quality) into a single soybean variety through genetic engineering. By using multiple engineered nuclease targets or stacking transgenes, the invention combines several functions into one unified genetic modification event, simplifying the breeding program while achieving superior agronomic performance across multiple parameters simultaneously.
3Manufacturing precision
If genome editing using engineered nucleases is employed, then precision of trait introduction is enhanced, but regulatory and safety considerations increase
Solution Approach 1:
The patent applies genome editing at specific, localized genomic loci rather than random mutations. Engineered nucleases are designed to target precise DNA sequences adjacent to endogenous genes of interest, enabling focused modifications only where needed. This localized approach minimizes off-target effects and reduces regulatory concerns compared to whole-genome random mutagenesis, while maintaining high precision in trait introduction.
Data Source
AI summary
The invention relates to the soybean variety designated 01106137. Provided by the invention are the seeds, plants and derivatives of the soybean variety 01106137. Also provided by the invention are tissue cultures of the soybean variety 01106137 and the plants regenerated therefrom. Still further provided by the invention are methods for producing soybean plants by crossing the soybean variety 01106137 with itself or another soybean variety and plants produced by such methods.