Soybean Variety 01106460 for Faster Multi-Trait Breeding

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Solution Overview

Problem

Existing soybean varieties lack improved combinations of traits such as higher seed yield, disease resistance, herbicide tolerance, and nutritional quality, making it challenging to develop stable and high-yielding soybean varieties that meet agronomic and nutritional demands.

Innovation Solution

Development of the novel soybean variety 01106460, which incorporates genetic modifications and locus conversions for traits like glyphosate, glufosinate, and dicamba tolerance, as well as resistance to diseases and insects, through methods such as genetic transformation and genome editing using engineered nucleases, and breeding techniques like backcrossing and pedigree breeding.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Productivity

If conventional breeding methods are used to develop soybean varieties, then genetic diversity can be maintained, but the development of stable high-yielding varieties with multiple improved traits takes excessive time and generations

Engineering Contradiction:
Improvebreeding efficiencyVSAvoidtime to develop new variety
Core Design Contradiction:
ProductivityVSLoss of time

Solution Approach 1:

The patent applies preliminary action by pre-modifying parental lines with desired traits (herbicide tolerance, disease resistance, nutritional quality) before crossing. This allows the F1 generation to inherit multiple improved traits simultaneously, eliminating the need for multiple generations of selective breeding and significantly accelerating variety development.

Inventive Principle:
Principle #10Preliminary action

Solution Approach 2:

The patent employs parameter changes by introducing specific genetic modifications in parental lines that alter key parameters such as herbicide tolerance levels, disease resistance profiles, and nutritional composition. These pre-established parameter changes are directly transmitted to progeny, achieving rapid improvement without traditional iterative selection.

Inventive Principle:
Principle #35Parameter changes

2Adaptability or versatility

If multiple traits are combined in a single variety through conventional breeding, then agronomic performance improves, but the complexity of the breeding program and selection process increases significantly

Engineering Contradiction:
Improvecombination of traitsVSAvoidbreeding program complexity
Core Design Contradiction:
Adaptability or versatilityVSDevice complexity

Solution Approach 1:

The patent merges multiple desirable traits into single parental lines through genetic modification before crossing. This consolidation approach allows the F1 progeny to inherit a comprehensive package of improved traits (herbicide tolerance, disease resistance, nutritional quality) in a single generation, greatly simplifying the breeding program structure and selection requirements.

Inventive Principle:
Principle #5Merging (Combining)

Solution Approach 2:

The patent creates universal parental lines that possess multiple functions simultaneously - herbicide tolerance, disease resistance, and improved nutritional quality. These multi-functional parental lines serve as efficient sources for generating improved varieties, reducing the need for separate breeding programs for each trait.

Inventive Principle:
Principle #6Universality (Multi-functionality)

3Loss of time

If genetic modification techniques are used to introduce specific traits, then breeding time is reduced, but the complexity of genetic transformation and genome editing increases

Engineering Contradiction:
Improvetime to introduce traitVSAvoidgenetic transformation complexity
Core Design Contradiction:
Loss of timeVSDevice complexity

Solution Approach 1:

The patent extracts and isolates specific genes or genetic regions responsible for desired traits (such as herbicide tolerance genes or disease resistance genes) and introduces them into parental lines through transformation. This targeted approach allows efficient introduction of single traits or small numbers of traits without requiring complex whole-genome modifications, thereby reducing transformation complexity while maintaining speed.

Inventive Principle:
Principle #2Taking out (Extraction)

4Productivity

If existing soybean varieties are used, then current agronomic practices can be maintained, but yield potential and nutritional quality remain suboptimal

Engineering Contradiction:
Improveseed yieldVSAvoidstability of variety performance
Core Design Contradiction:
ProductivityVSReliability

Solution Approach 1:

The patent applies preliminary action by pre-establishing genetic stability in parental lines through multiple generations of selfing or backcrossing before introducing desired traits. This ensures that the F1 progeny inherit both the improved traits and stable genetic backgrounds, achieving simultaneous improvement in yield potential and performance reliability without requiring additional stabilization generations.

Inventive Principle:
Principle #10Preliminary action

Data Source

PatentUS12457988B2Soybean variety 01106460
Publication Date: 2025.11.04 MONSANTO TECHNOLOGY LLC

AI summary

The invention relates to the soybean variety designated 01106460. Provided by the invention are the seeds, plants and derivatives of the soybean variety 01106460. Also provided by the invention are tissue cultures of the soybean variety 01106460 and the plants regenerated therefrom. Still further provided by the invention are methods for producing soybean plants by crossing the soybean variety 01106460 with itself or another soybean variety and plants produced by such methods.