Soybean Variety 4423586 Genetic Modification for Trait Predictability

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Solution Overview

Problem

The development of new soybean varieties is a time-consuming and unpredictable process due to the complexity of combining desirable traits like disease resistance, yield, and environmental adaptability, making it challenging for breeders to consistently produce superior varieties using conventional breeding methods.

Innovation Solution

The introduction of the soybean variety 4423586, which can be crossed with itself or other plants to produce hybrid seeds and plants with specific desirable traits such as herbicide resistance, disease resistance, and improved nutritional quality, using methods like backcrossing and genetic transformation to introduce desired loci while maintaining the variety's morphological and physiological characteristics.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If conventional breeding methods are used to combine desirable traits, then variety development is achieved, but the process is time-consuming and unpredictable

Engineering Contradiction:
Improvepredictability of variety developmentVSAvoidtime required for variety development
Core Design Contradiction:
ReliabilityVSLoss of time

Solution Approach 1:

The patent replaces conventional mechanical breeding methods with genetic engineering techniques. Specifically, it uses gene targeting and DNA manipulation to introduce desired traits directly into the soybean genome, eliminating the need for repeated crossing and selection cycles that characterize traditional breeding. This substitution of biological mechanisms enables predictable trait introduction without the time loss inherent in conventional methods.

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

Solution Approach 2:

The patent applies preliminary action by pre-characterizing the genomic loci for desirable traits before actual variety development. The inventors have identified and characterized specific gene locations (such as those conferring disease resistance or improved yield) in advance, allowing these traits to be introduced directly into the soybean genome through targeted genetic modification, rather than discovering and selecting for them during the breeding process.

Inventive Principle:
Principle #10Preliminary action

2Adaptability or versatility

If multiple desirable traits are combined in a single variety, then agronomic quality improves, but the complexity of inheritance makes this difficult to achieve

Engineering Contradiction:
Improvecombination of desirable traitsVSAvoidcomplexity of inheritance
Core Design Contradiction:
Adaptability or versatilityVSDevice complexity

Solution Approach 1:

The patent applies segmentation by treating each desirable trait as a separate, identifiable genetic component. Instead of attempting to combine multiple traits through complex breeding operations, the inventors segment the genetic material and introduce each desired trait (disease resistance, yield, environmental adaptability) as distinct genetic elements that can be independently controlled and combined in the modified variety.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The patent utilizes parameter changes by modifying the genetic parameters of the soybean variety through controlled DNA manipulation. By changing the genetic parameters at specific loci (inserting, deleting, or modifying genes), the inventors achieve the combination of multiple desirable traits without being constrained by the complex inheritance patterns that would arise from traditional crossing of multiple parents.

Inventive Principle:
Principle #35Parameter changes

3Measurement precision

If true genotypic value is identified, then superior plants can be selected, but environmental factors mask the true genetic worth

Engineering Contradiction:
Improveaccuracy of genotypic value identificationVSAvoidenvironmental masking of genetic traits
Core Design Contradiction:
Measurement precisionVSObject-affected harmful factors

Solution Approach 1:

The patent applies the taking out principle by extracting the genetic information for desirable traits from the complex phenotypic expression that is influenced by environmental factors. Through direct genomic analysis and DNA sequencing, the inventors can identify the presence of specific genes (such as those for disease resistance or improved protein content) regardless of environmental conditions, thereby measuring true genotypic value without the masking effects of the environment.

Inventive Principle:
Principle #2Taking out (Extraction)

Data Source

PatentUS7414176B2Soybean variety 4423586
Publication Date: 2008.08.19 MONSANTO TECHNOLOGY LLC

AI summary

The invention relates to the soybean variety designated 4423586. Provided by the invention are the seeds, plants and derivatives of the soybean variety 4423586. Also provided by the invention are tissue cultures of the soybean variety 4423586 and the plants regenerated therefrom. Still further provided by the invention are methods for producing soybean plants by crossing the soybean variety 4423586 with itself or another soybean variety and plants produced by such methods.