Soybean Variety 01094778 for Faster Multi-Trait Breeding

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Solution Overview

Problem

Existing soybean varieties lack improved combinations of traits such as higher seed yield, disease resistance, insect resistance, drought and heat tolerance, better agronomic quality, and herbicide resistance, which are essential for maximizing grain production and meeting the demands of food and animal feed.

Innovation Solution

Development of the novel soybean variety 01094778, which incorporates genetic modifications and cross-breeding techniques to enhance traits like herbicide resistance, disease resistance, and improved nutritional quality, utilizing methods like genome editing with engineered nucleases and traditional breeding practices.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Productivity

If traditional breeding practices are used to develop soybean varieties, then genetic diversity is maintained, but the rate of improvement in multiple traits simultaneously is limited

Engineering Contradiction:
Improveseed yieldVSAvoidbreeding time
Core Design Contradiction:
ProductivityVSLoss of time

Solution Approach 1:

The patent combines traditional cross-breeding methods with modern genome editing technologies (engineered nucleases) to simultaneously achieve genetic diversity maintenance and accelerated trait improvement. This integration allows multiple desirable traits to be incorporated faster than conventional breeding alone would permit.

Inventive Principle:
Principle #5Merging (Combining)

Solution Approach 2:

The patent employs engineered nucleases to precisely modify genomic parameters at specific loci, enabling rapid introduction of herbicide resistance, disease resistance, and nutritional quality traits without the time-consuming process of traditional sequential breeding.

Inventive Principle:
Principle #35Parameter changes

2Reliability

If multiple trait improvements are pursued simultaneously, then variety performance is enhanced, but breeding program complexity increases

Engineering Contradiction:
Improvedisease resistanceVSAvoidbreeding program complexity
Core Design Contradiction:
ReliabilityVSDevice complexity

Solution Approach 1:

The breeding program is segmented into distinct modules: traditional cross-breeding for genetic diversity, engineered nuclease applications for specific trait insertion, and selective breeding for trait consolidation. This segmentation allows each component to be optimized independently while managing overall program complexity.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The patent uses molecular markers and genomic selection as intermediary tools to track and select for multiple traits simultaneously, reducing the complexity of phenotypic evaluation and enabling more efficient multi-trait breeding programs.

Inventive Principle:
Principle #24Intermediary (Mediator)

3Manufacturing precision

If genome editing with engineered nucleases is used, then trait insertion precision is improved, but technical requirements and costs increase

Engineering Contradiction:
Improvegenetic modification precisionVSAvoidbreeding process simplicity
Core Design Contradiction:
Manufacturing precisionVSEase of manufacture

Solution Approach 1:

The patent performs preliminary characterization of target genomic loci and prepares engineered nuclease constructs in advance, allowing precise trait insertion when needed. This preliminary preparation offsets the technical complexity during actual breeding operations.

Inventive Principle:
Principle #10Preliminary action

Solution Approach 2:

The patent uses transient expression systems and disposable transformation protocols where engineered nucleases are introduced temporarily to create the desired genetic modification, then removed. This approach achieves high precision without requiring permanent complex infrastructure.

Inventive Principle:
Principle #27Cheap short-living objects (Disposable)

Data Source

PatentUS12593793B2Soybean variety 01094778
Publication Date: 2026.04.07 MONSANTO TECHNOLOGY LLC

AI summary

The invention relates to the soybean variety designated 01094778. Provided by the invention are the seeds, plants and derivatives of the soybean variety 01094778. Also provided by the invention are tissue cultures of the soybean variety 01094778 and the plants regenerated therefrom. Still further provided by the invention are methods for producing soybean plants by crossing the soybean variety 01094778 with itself or another soybean variety and plants produced by such methods.