Soybean Cultivar CL1922650 Marker-Assisted Breeding

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Solution Overview

Problem

Soybean breeding is hindered by the genetic complexity and self-pollination nature of soybeans, making it challenging to develop new cultivars with desired traits such as herbicide resistance, disease resistance, and improved yield potential, which requires intensive research and development and often results in unpredictable outcomes.

Innovation Solution

The development of soybean cultivars like CL1920832, CL1922439, CL1922500, CL1922511, CL1922568, CL1922578, CL1922596, CL1922616, CL1922650, CL1922757, and CL1922868, which incorporate transgenes for herbicide resistance, disease resistance, and modified fatty acid profiles, using techniques like genetic transformation and marker-assisted selection to introduce specific traits and improve breeding efficiency.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If traditional breeding methods are used to develop new soybean cultivars, then genetic diversity is maintained through self-pollination, but the breeding process becomes highly unpredictable and requires intensive research and development

Engineering Contradiction:
Improvepredictability of breeding outcomesVSAvoidbreeding program complexity
Core Design Contradiction:
ReliabilityVSDevice complexity

Solution Approach 1:

The patent uses molecular markers as intermediaries to bridge the gap between phenotypic selection and genotypic prediction. These markers serve as reliable indicators of desired traits, allowing breeders to predict breeding outcomes with high accuracy before actual trait expression occurs, thereby resolving the contradiction between reliability and complexity

Inventive Principle:
Principle #24Intermediary (Mediator)

Solution Approach 2:

The patent replaces traditional mechanical phenotypic selection methods with molecular marker-based selection. Instead of visually assessing traits in the field, breeders use DNA markers to directly detect the presence of desired alleles, substituting a more precise and predictable molecular system for the unreliable mechanical observation system

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

2Productivity

If marker-assisted selection is implemented to improve breeding efficiency, then specific traits can be more accurately selected, but the technical complexity of the breeding program increases

Engineering Contradiction:
Improvebreeding efficiencyVSAvoidbreeding program complexity
Core Design Contradiction:
ProductivityVSDevice complexity

Solution Approach 1:

The patent segments the breeding process into distinct phases: marker development, marker validation, and marker-assisted selection. By dividing the complex breeding program into manageable segments with clearly defined objectives and protocols, the patent maintains high productivity while controlling overall program complexity through systematic organization

Inventive Principle:
Principle #1Segmentation

3Adaptability or versatility

If transgenes are introduced to provide herbicide resistance and disease resistance, then commercial appeal and environmental adaptability improve, but the genetic complexity of the cultivar increases

Engineering Contradiction:
Improveenvironmental adaptabilityVSAvoidgenetic complexity
Core Design Contradiction:
Adaptability or versatilityVSDevice complexity

Solution Approach 1:

The patent extracts the complexity of transgene development and integration by using pre-characterized marker systems that track transgene inheritance. Instead of managing the full complexity of transgene expression and regulation, the breeding program focuses on selecting for marker alleles that reliably indicate the presence of desired transgenes, thereby improving adaptability while managing genetic complexity

Inventive Principle:
Principle #2Taking out (Extraction)

Data Source

PatentUS12089558B2Soybean variety CL1922650
Publication Date: 2024.09.17 SYNGENTA CROP PROTECITON AG

AI summary

The present invention is directed in part to soybean variety CL1920832, CL1922439, CL1922500, CL1922511, CL1922568, CL1922578, CL1922596, CL1922616, CL1922650, CL1922757, and/or CL1922868 breeding and development. The present invention particularly relates to soybean variety CL1920832, CL1922439, CL1922500, CL1922511, CL1922568, CL1922578, CL1922596, CL1922616, CL1922650, CL1922757, and/or CL1922868 and its seed, cells, germplasm, plant parts, and progeny, and methods of using CL1920832, CL1922439, CL1922500, CL1922511, CL1922568, CL1922578, CL1922596, CL1922616, CL1922650, CL1922757, and/or CL1922868, e.g., in a breeding program.