Soybean Variety CL1941276 With Site-Specific Trait Integration

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Solution Overview

Problem

The development of new soybean cultivars is unpredictable and requires intensive research due to vast genetic diversity and self-pollination, making it challenging to produce consistent and desirable traits such as disease resistance, insect resistance, and environmental adaptability efficiently.

Innovation Solution

The introduction of transgenic genes and site-specific recombination systems like FRT and Cre/Lox into soybean cultivars CL1941276, CL1941547, CL1941920, CL1941244, and CL1941256 to confer traits like herbicide resistance, fungal resistance, and altered oil profiles, combined with breeding methods like marker-assisted selection and backcrossing to achieve desired genetic combinations.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Adaptability or versatility

If traditional breeding methods are used to develop new soybean cultivars, then genetic diversity is maintained, but the process becomes unpredictable and requires intensive research

Engineering Contradiction:
Improvegenetic diversityVSAvoidpredictability of trait development
Core Design Contradiction:
Adaptability or versatilityVSReliability

Solution Approach 1:

Site-specific recombination systems (FRT, Cre/Lox) act as intermediaries to enable precise genetic modifications. These systems allow breeders to introduce specific traits at predetermined locations in the genome, serving as a mediator between traditional breeding and genetic engineering approaches, thereby achieving both genetic diversity and predictability

Inventive Principle:
Principle #24Intermediary (Mediator)

Solution Approach 2:

The patent establishes predetermined genetic loci with site-specific recombination sites before breeding begins. This preliminary preparation allows for controlled introduction of desired traits later in the breeding process, making the outcome predictable while maintaining genetic diversity through selective combination of traits

Inventive Principle:
Principle #10Preliminary action

2Adaptability or versatility

If multiple desired traits are introduced into soybean cultivars, then resistance and nutritional qualities are enhanced, but the breeding process complexity increases

Engineering Contradiction:
Improvenumber of desired traitsVSAvoidbreeding process complexity
Core Design Contradiction:
Adaptability or versatilityVSDevice complexity

Solution Approach 1:

The breeding process is segmented into distinct modular steps: establishing base lines with specific recombination sites, introducing individual traits through controlled crosses, and combining multiple traits in subsequent generations. This segmentation allows complex multi-trait development to be managed as a series of simpler, controlled operations

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

Site-specific recombination systems serve as intermediaries that simplify the integration of multiple traits. By providing predetermined insertion sites, these systems eliminate the need for complex random insertion processes, making multi-trait breeding more systematic and manageable

Inventive Principle:
Principle #24Intermediary (Mediator)

3Stability of the object's composition

If self-pollination is utilized in soybean breeding, then genetic stability is maintained, but cross-pollination efficiency is reduced

Engineering Contradiction:
Improvegenetic stabilityVSAvoidcross-pollination efficiency
Core Design Contradiction:
Stability of the object's compositionVSProductivity

Solution Approach 1:

The patent establishes inbred lines with predetermined site-specific recombination sites before crossing. This preliminary genetic stabilization ensures that when cross-pollination occurs, the background genetics are stable and uniform, allowing efficient selection of offspring with desired trait combinations while maintaining overall genetic stability

Inventive Principle:
Principle #10Preliminary action

Data Source

PatentUS20250261606A1Soybean variety CL1941276
Publication Date: 2025.08.21 SYNGENTA CROP PROTECITON AG

AI summary

The present invention is directed in part to soybean variety CL1941276, CL1941547, CL1941920, CL1941244, and/or CL1941256 breeding and development. The present invention particularly relates to soybean variety CL1941276, CL1941547, CL1941920, CL1941244, and/or CL1941256 and its seed, cells, germplasm, plant parts, and progeny, and methods of using CL1941276, CL1941547, CL1941920, CL1941244, and/or CL1941256, e.g., in a breeding program.