Soybean Cultivar CS1660404 Site-Specific Recombination Trait Integration

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Solution Overview

Problem

Soybean breeding is complex due to self-pollination, requiring intervention for cross-pollination and extensive research to develop new cultivars with desired traits like herbicide resistance, disease resistance, and improved yield, which is time-consuming and unpredictable.

Innovation Solution

Development of soybean cultivar CS1660404 and CS1763636 with transgenic traits such as herbicide resistance, disease resistance, and modified fatty acid profiles, utilizing single locus conversion and site-specific recombination systems for integrating desired traits into the soybean genome.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If traditional breeding methods are used to develop new soybean cultivars with desired traits, then genetic diversity and trait integration are achieved, but the process becomes time-consuming and unpredictable

Engineering Contradiction:

Improvepredictability of cultivar developmentVSAvoidtime required for breeding

Core Design Contradiction:

ReliabilityVSLoss of time

Solution Approach 1:

The patent replaces traditional mechanical breeding methods (manual cross-pollination, selection, and crossing) with genetic engineering techniques. Specifically, site-specific recombination systems enable precise insertion of desired traits directly into the genome, eliminating the need for multiple generations of conventional breeding and significantly reducing development time while increasing predictability

Inventive Principle:

Principle #28Mechanics substitution (Replace mechanical system)

Solution Approach 2:

The patent introduces site-specific recombination systems as intermediary mechanisms that facilitate precise genetic modification. These systems act as mediators between the desired trait genes and the soybean genome, enabling controlled integration at specific loci rather than random insertion, thereby improving both speed and reliability of trait development

Inventive Principle:

Principle #24Intermediary (Mediator)

2Adaptability or versatility

If cross-pollination intervention is required for soybean breeding, then new genetic combinations are created, but the process complexity increases

Engineering Contradiction:

Improvegenetic combination diversityVSAvoidbreeding process complexity

Core Design Contradiction:

Adaptability or versatilityVSDevice complexity

Solution Approach 1:

The patent replaces complex manual cross-pollination procedures with direct genetic engineering approaches. Site-specific recombination systems allow desired traits to be integrated into the genome without requiring manual emasculation, pollination, and multi-generational crossing, thereby maintaining genetic diversity while dramatically simplifying the breeding process

Inventive Principle:

Principle #28Mechanics substitution (Replace mechanical system)

Solution Approach 2:

The patent extracts the essential function of creating genetic diversity from the complex cross-pollination process and achieves it through direct genetic modification. By taking out the need for manual breeding operations and using targeted gene insertion, the system maintains adaptability while reducing process complexity

Inventive Principle:

Principle #2Taking out (Extraction)

Data Source

PatentUS11678632B2Soybean variety

Publication Date: 2023.06.20 SYNGENTA CROP PROTECITON AG

AI summary

The present invention is directed in part to soybean variety CS1660404 and/or CS1763636 breeding and development. The present invention particularly relates to soybean variety CS1660404 and/or CS1763636 and its seed, cells, germplasm, plant parts, and progeny, and methods of using CS1660404 and/or CS1763636, e.g., in a breeding program.