Soybean D4021792 Breeding via Marker-Assisted Selection

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Solution Overview

Problem

The development of new soybean varieties is a time-consuming and unpredictable process due to the complexity of combining desirable traits like disease resistance, yield, and environmental adaptability, with conventional breeding methods lacking control at the DNA level, leading to high research costs and variability in results.

Innovation Solution

The soybean variety D4021792 is developed through specific breeding methods, including backcrossing and genetic transformation, to introduce desired traits such as herbicide resistance, disease resistance, and improved nutritional quality, allowing for controlled introduction of genetic loci and predictable trait inheritance.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Adaptability or versatility

If conventional breeding methods are used to combine desirable traits, then genetic diversity is achieved, but the process is time-consuming and unpredictable

Engineering Contradiction:
Improvetrait combination capabilityVSAvoidbreeding cycle duration
Core Design Contradiction:
Adaptability or versatilityVSLoss of time

Solution Approach 1:

The patent replaces conventional mechanical breeding methods (manual crossing, selection, and evaluation) with molecular marker technology and DNA-level analysis. This substitution enables direct identification of desired genetic traits without waiting for phenotypic expression, dramatically reducing the breeding cycle from multiple years to a fraction of that time while maintaining genetic diversity and trait combination capabilities.

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

Solution Approach 2:

The patent introduces molecular markers as intermediary tools that serve as proxies for desired traits. These markers act as mediators between the breeder and the actual genetic traits, allowing selection based on DNA sequences rather than waiting for complex phenotypic expressions. This intermediary approach accelerates the breeding process by enabling early-generation selection with high accuracy.

Inventive Principle:
Principle #24Intermediary (Mediator)

2Adaptability or versatility

If conventional breeding methods are used, then natural genetic recombination occurs, but control at the DNA level is lacking

Engineering Contradiction:
Improvegenetic recombinationVSAvoidDNA level control
Core Design Contradiction:
Adaptability or versatilityVSManufacturing precision

Solution Approach 1:

The patent replaces random natural recombination with marker-assisted selection that operates at the DNA level. By using molecular markers linked to desired traits, the breeding process gains precise control over which genetic combinations are selected, transforming an uncontrollable biological process into a precisely managed genetic engineering approach.

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

Solution Approach 2:

The patent implements feedback mechanisms through molecular marker analysis that provide real-time information about the genetic composition of breeding lines. This feedback allows breeders to make informed decisions at each generation, adjusting selection criteria based on actual genetic data rather than phenotypic observations, thereby achieving precise control over DNA-level outcomes.

Inventive Principle:
Principle #23Feedback

3Stability of the object's composition

If repeated selfing and selection are performed to develop varieties, then trait stability is achieved, but unpredictability remains due to environmental factors

Engineering Contradiction:
Improvetrait consistencyVSAvoidprediction accuracy
Core Design Contradiction:
Stability of the object's compositionVSReliability

Solution Approach 1:

The patent uses molecular markers as intermediaries that directly reflect the genetic basis of traits without being influenced by environmental factors. This approach separates genetic determination from phenotypic expression, allowing accurate prediction of trait inheritance based on DNA sequences alone, thereby eliminating the unpredictability introduced by environmental variability during the breeding process.

Inventive Principle:
Principle #24Intermediary (Mediator)

Data Source

PatentUS7700843B2Soybean variety D4021792
Publication Date: 2010.04.20 MONSANTO TECHNOLOGY LLC

AI summary

The invention relates to the soybean variety designated D4021792. Provided by the invention are the seeds, plants and derivatives of the soybean variety D4021792. Also provided by the invention are tissue cultures of the soybean variety D4021792 and the plants regenerated therefrom. Still further provided by the invention are methods for producing soybean plants by crossing the soybean variety D4021792 with itself or another soybean variety and plants produced by such methods.