Soybean Germplasm Breeding With Single-Locus Trait Conversion

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Solution Overview

Problem

The development of new soybean germplasm is highly unpredictable due to vast genetic diversity and requires intensive research and development, with existing breeding methods being inefficient in producing consistent and desirable traits such as disease resistance, insect resistance, and yield improvement.

Innovation Solution

The introduction of transgenes and single locus conversions in soybean varieties CL1942258, CL1943627, and/or CL1943668, along with breeding techniques like marker-assisted selection and backcrossing, to incorporate traits such as herbicide resistance, fungal resistance, and modified fatty acid profiles, while maintaining the morphological and physiological characteristics of the soybean.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Adaptability or versatility

If traditional breeding methods are used to develop new soybean germplasm, then genetic diversity is maintained, but the process becomes highly unpredictable and requires intensive research and development

Engineering Contradiction:
Improvegenetic diversityVSAvoidbreeding development time
Core Design Contradiction:
Adaptability or versatilityVSLoss of time

Solution Approach 1:

The patent applies parameter changes by modifying specific genetic loci through transgene introduction and single locus conversion techniques. Instead of relying on traditional breeding that explores vast genetic diversity unpredictably, the invention precisely alters specific genetic parameters (loci) to achieve desired traits such as herbicide resistance and modified fatty acid profiles, significantly reducing breeding development time while maintaining genetic diversity in other regions of the genome.

Inventive Principle:
Principle #35Parameter changes

2Productivity

If transgenes and single locus conversions are introduced to incorporate specific traits, then breeding efficiency is improved, but the genetic complexity of the soybean increases

Engineering Contradiction:
Improvebreeding efficiencyVSAvoidgenetic complexity
Core Design Contradiction:
ProductivityVSDevice complexity

Solution Approach 1:

The patent applies the extraction principle by isolating and modifying specific genetic loci independently from the rest of the genome. Through single locus conversion and targeted transgene introduction, the invention extracts only the necessary genetic changes required for desired traits (herbicide resistance, fatty acid modification) without introducing unnecessary genetic complexity elsewhere in the genome, thus improving breeding efficiency while minimizing overall genetic complexity.

Inventive Principle:
Principle #2Taking out (Extraction)

3Manufacturing precision

If multiple breeding techniques are combined to achieve desired traits, then trait incorporation is more accurate, but the manufacturing process becomes more complex

Engineering Contradiction:
Improvetrait incorporation accuracyVSAvoidbreeding process complexity
Core Design Contradiction:
Manufacturing precisionVSDevice complexity

Solution Approach 1:

The patent applies segmentation by dividing the breeding process into distinct, manageable stages: (1) selection of parental lines with desired traits, (2) controlled crossing to combine traits, (3) marker-assisted selection to track specific loci, (4) single locus conversion for precise trait incorporation, and (5) validation of desired characteristics. This segmented approach improves trait incorporation accuracy while making the overall breeding process more systematic and less complex.

Inventive Principle:
Principle #1Segmentation

Data Source

PatentUS20250241265A1Soybean variety
Publication Date: 2025.07.31 SYNGENTA CROP PROTECITON AG

AI summary

The present invention is directed in part to soybean variety CL1942258, CL1943627, and/or CL1943668 breeding and development. The present invention particularly relates to soybean variety CL1942258, CL1943627, and/or CL1943668 and its seed, cells, germplasm, plant parts, and progeny, and methods of using CL1942258, CL1943627, and/or CL1943668, e.g., in a breeding program.