Soybean Variety Breeding With Marker-Assisted Multi-Trait Selection

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Solution Overview

Problem

Existing soybean varieties lack improved combinations of traits such as higher seed yield, disease resistance, insect resistance, drought and heat tolerance, better agronomic quality, and herbicide resistance, which are essential for maximizing grain production and meeting food demands.

Innovation Solution

Development of the novel soybean variety 01098336, which includes genetic modifications for herbicide resistance, disease resistance, and improved nutritional quality, achieved through methods like genome editing using engineered nucleases, and breeding techniques such as backcrossing and recurrent selection.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If conventional breeding methods are used to develop soybean varieties, then genetic diversity can be maintained, but breeding time and complexity increase significantly

Engineering Contradiction:
Improvegenetic diversityVSAvoidbreeding time
Core Design Contradiction:
ReliabilityVSLoss of time

Solution Approach 1:

The patent employs molecular markers as intermediary tools to bridge the gap between conventional breeding and genetic selection. These markers serve as mediators that allow breeders to track and select for desirable traits without requiring lengthy traditional breeding cycles, thus maintaining genetic diversity while reducing breeding time.

Inventive Principle:
Principle #24Intermediary (Mediator)

Solution Approach 2:

The invention changes the parameter of selection precision by introducing molecular marker-assisted selection. This allows for precise identification and selection of plants with desired genetic traits at the molecular level, dramatically accelerating the breeding process while maintaining genetic diversity through targeted selection.

Inventive Principle:
Principle #35Parameter changes

2Productivity

If multiple traits are combined in a single variety, then agronomic performance improves, but breeding program complexity increases

Engineering Contradiction:
Improveagronomic performanceVSAvoidbreeding program complexity
Core Design Contradiction:
ProductivityVSDevice complexity

Solution Approach 1:

The patent applies segmentation by breaking down the complex task of combining multiple traits into manageable segments through molecular marker-assisted selection. Each desired trait can be tracked and selected independently using specific molecular markers, allowing breeders to systematically combine multiple traits without overwhelming program complexity.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The invention creates universal breeding tools through molecular markers that can be applied across multiple traits and breeding programs. These markers serve multiple functions including trait identification, purity testing, and genetic diversity assessment, thereby improving agronomic performance while standardizing and simplifying breeding program complexity.

Inventive Principle:
Principle #6Universality (Multi-functionality)

3Productivity

If selection pressure is increased to improve yield, then productivity increases, but genetic diversity may be reduced

Engineering Contradiction:
ImproveyieldVSAvoidgenetic diversity
Core Design Contradiction:
ProductivityVSReliability

Solution Approach 1:

The patent implements feedback mechanisms through molecular marker monitoring that provide real-time information about genetic diversity during the selection process. This feedback allows breeders to adjust selection pressure to maintain desired yield improvements while preserving adequate genetic diversity by identifying and retaining plants with both high yield potential and diverse genetic backgrounds.

Inventive Principle:
Principle #23Feedback

Data Source

PatentUS12616152B2Soybean variety 01098336
Publication Date: 2026.05.05 MONSANTO TECHNOLOGY LLC

AI summary

The invention relates to the soybean variety designated 01098336. Provided by the invention are the seeds, plants and derivatives of the soybean variety 01098336. Also provided by the invention are tissue cultures of the soybean variety 01098336 and the plants regenerated therefrom. Still further provided by the invention are methods for producing soybean plants by crossing the soybean variety 01098336 with itself or another soybean variety and plants produced by such methods.