Soybean Germplasm Breeding With Marker-Assisted Trait Introgression

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Solution Overview

Problem

The development of new soybean cultivars is unpredictable and requires intensive research due to vast genetic diversity and complex traits, making it challenging to produce consistent and commercially viable soybean germplasm with desired characteristics such as disease resistance, insect resistance, and altered oil profiles.

Innovation Solution

The introduction of transgenic genes and single locus conversions in soybean varieties CL1945910, CL1945851, CL1924220, CL1924371, CL1946032, CL1946267, CL1946273, CL1946369, CL1946309, CL1946320, CL1946388, and/or CL1946410, CL1946167, which confer traits like herbicide resistance, fungal resistance, insect resistance, and altered oil profiles, along with breeding methods like marker-assisted selection and backcrossing to achieve desired genetic combinations.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If traditional breeding methods are used to develop new soybean cultivars, then genetic diversity and complexity are maintained, but the process becomes unpredictable and time-consuming

Engineering Contradiction:
Improvepredictability of cultivar developmentVSAvoidbreeding cycle duration
Core Design Contradiction:
ReliabilityVSLoss of time

Solution Approach 1:

The patent applies preliminary action by using marker-assisted selection to identify and select plants with desired traits before completing the full breeding cycle. Molecular markers are used to predict the presence of desirable genes (such as disease resistance, insect resistance, or altered oil profiles) early in the breeding process, allowing breeders to make informed selections without waiting for phenotypic expression, thereby reducing the time required to develop new cultivars while improving predictability.

Inventive Principle:
Principle #10Preliminary action

2Manufacturing precision

If marker-assisted selection is employed to introduce desired traits, then breeding precision is improved, but the complexity of the breeding program increases

Engineering Contradiction:
Improveprecision of trait introductionVSAvoidbreeding program complexity
Core Design Contradiction:
Manufacturing precisionVSDevice complexity

Solution Approach 1:

The patent uses molecular markers as intermediaries between the desired traits and the breeding process. These markers serve as detectable proxies for the actual genes of interest, allowing breeders to select plants based on marker presence rather than directly observing the trait. This intermediary approach enables precise trait introduction through DNA-based selection while managing complexity by providing clear, objective criteria for selection decisions.

Inventive Principle:
Principle #24Intermediary (Mediator)

3Manufacturing precision

If backcrossing is used to transfer specific genes, then the desired traits are achieved with higher accuracy, but the number of generations required increases

Engineering Contradiction:
Improveaccuracy of trait transferVSAvoidnumber of breeding generations
Core Design Contradiction:
Manufacturing precisionVSDuration of action of moving object

Solution Approach 1:

The patent applies preliminary action by using molecular markers to identify and select plants with the desired backcrossing traits early in the process. Instead of waiting for multiple generations for phenotypic expression, markers allow breeders to identify plants carrying the desired genes immediately after the backcross, enabling accelerated selection and reducing the number of generations required to achieve accurate trait transfer.

Inventive Principle:
Principle #10Preliminary action

Data Source

PatentUS12520795B2Soybean variety
Publication Date: 2026.01.13 SYNGENTA CROP PROTECITON AG

AI summary

The present invention is directed in part to soybean variety CL1945910, CL1945851, CL1924220, CL1924371, CL1946032, CL1946267, CL1946273, CL1946369, CL1946309, CL1946320, CL1946388, CL1946410, and/or CL1946167 breeding and development. The present invention particularly relates to soybean variety CL1945910, CL1945851, CL1924220, CL1924371, CL1946032, CL1946267, CL1946273, CL1946369, CL1946309, CL1946320, CL1946388, CL1946410, and/or CL1946167 and its seed, cells, germplasm, plant parts, and progeny, and methods of using CL1945910, CL1945851, CL1924220, CL1924371, CL1946032, CL1946267, CL1946273, CL1946369, CL1946309, CL1946320, CL1946388, CL1946410, and/or CL1946167, e.g., in a breeding program.