Network Connection Determination in Sparse EEG Systems

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Solution Overview

Problem

Current methods for determining network connections in high-dimensional systems, particularly in EEG data, face challenges with accuracy and computational efficiency, leading to false positives and inability to handle sparse networks effectively.

Innovation Solution

A computer-implemented method that identifies probable zero connection coefficients and sets them to zero, improving parameter estimation by assuming sparseness in the network, reducing indirect links, and applying Granger-causality in high-dimensional systems.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Measurement precision

If existing methods (coherence, partial coherence, directed partial correlation) are used to determine network connections, then the coupling structure can be estimated, but the methods become unacceptably long or computationally demanding and lose accuracy when the network exceeds 10 nodes

Engineering Contradiction:
Improveaccuracy of connection estimationVSAvoidcomputational efficiency
Core Design Contradiction:
Measurement precisionVSProductivity

Solution Approach 1:

The method segments the network analysis by first identifying and removing indirect links through coherence and partial coherence calculations, then separately estimating direct connection coefficients. This segmentation allows the complex high-dimensional problem to be broken into manageable steps that maintain accuracy while improving computational efficiency

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The method performs preliminary identification of probable zero connection coefficients using coherence and partial coherence thresholds before the main parameter estimation. This preliminary action removes indirect links in advance, reducing the dimensionality of the subsequent estimation problem and preventing computational burden from increasing with network size

Inventive Principle:
Principle #10Preliminary action

2Reliability

If existing methods are used to determine network connections in high-dimensional systems, then connections can be identified, but false positives increase and the ability to handle sparse networks effectively is lost

Engineering Contradiction:
Improvereliability of connection identificationVSAvoidfalse positives in connection detection
Core Design Contradiction:
ReliabilityVSLoss of information

Solution Approach 1:

The method performs preliminary filtering by calculating coherence and partial coherence and identifying probable zero connection coefficients before main estimation. This preliminary action removes indirect links and reduces false positives by establishing a cleaner set of candidate connections for subsequent Granger-causality analysis

Inventive Principle:
Principle #10Preliminary action

Solution Approach 2:

The method changes parameters by applying sparsity assumptions and thresholding connection coefficients. By setting probable zero coefficients to zero and focusing estimation on non-zero coefficients, the method improves reliability in high-dimensional sparse networks while reducing false positives

Inventive Principle:
Principle #35Parameter changes

3Quantity of substance

If the network dimension increases beyond 10 nodes, then more comprehensive coverage is achieved, but the methods start to significantly lose accuracy and become unacceptably long or computationally demanding

Engineering Contradiction:
Improvenumber of nodes in networkVSAvoidcomputational complexity
Core Design Contradiction:
Quantity of substanceVSDevice complexity

Solution Approach 1:

The method segments the computational task into distinct phases: identifying indirect links through coherence, removing them by setting coefficients to zero, and then estimating remaining direct connections. This segmentation prevents computational complexity from scaling poorly with network dimension

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The method changes the parameter space by assuming sparsity and setting many connection coefficients to zero. This parameter change reduces the effective dimensionality of the estimation problem, allowing the method to handle networks with many more than 10 nodes without becoming computationally intractable

Inventive Principle:
Principle #35Parameter changes

Data Source

PatentEP3399909B1Method and system for determining network connections
Publication Date: 2022.03.02 GENTING TAURX DIAGNOSTIC CENT SDN BHD
  • EP3399909B1 patent drawingFigure 1~2(b)
  • EP3399909B1 patent drawingFigure 3~4
  • EP3399909B1 patent drawingFigure 5

AI summary

This invention relates to methods and systems for determining network connections. It is particularly, but not exclusively, related to methods and systems for determining network connections in sparse networks, and has particular application to EEG data. An aspect of the invention provides a method for identifying, in a network of interacting nodes simultaneously producing signals,connections between said nodes andof estimating connection coefficients between nodesidentified as connected which includes the steps of setting to zero connection coefficients where the calculated coherence or partial coherence is below a first predetermined thresholdand subsequently setting to zero connection coefficients where the estimated connection coefficients are below a second predetermined threshold, and then re-estimatingthe connection coefficients for the combinations of nodes for which the connection coefficients have not already been set to zero.