Specimen Container Load Balancing for Stable Microbial Detection

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Solution Overview

Problem

Current automated detection systems for pathogenic microorganisms in biological fluids face inefficiencies in balancing the load of specimen containers across multiple detection apparatuses, leading to suboptimal processing times and temperature variations, which can impact the accuracy and speed of microbial growth detection.

Innovation Solution

An automated system and method for load balancing specimen containers between multiple detection apparatuses, involving a housing with holding and agitation structures, detection units, and a method that determines the loading capacity and transfer status of each apparatus to optimize container distribution based on available cell capacity and temperature control, ensuring efficient transfer and processing.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Productivity

If specimen containers are loaded into multiple automated detection apparatuses without load balancing, then the processing capacity is increased, but temperature variations and processing time inefficiencies occur

Engineering Contradiction:
Improveprocessing capacityVSAvoidtemperature control accuracy
Core Design Contradiction:
ProductivityVSManufacturing precision

Solution Approach 1:

The system continuously monitors the loading status, temperature, and processing capacity of each detection apparatus, using this feedback information to dynamically determine the optimal destination for incoming specimen containers. The controller adjusts distribution decisions based on real-time system state to maintain temperature control accuracy while maximizing processing capacity.

Inventive Principle:
Principle #23Feedback

Solution Approach 2:

The load balancing system dynamically adjusts the distribution of specimen containers based on changing system conditions such as current load, temperature stability, and processing speed of each apparatus. This dynamic adaptation allows the system to optimize both productivity and temperature control accuracy under varying operational conditions.

Inventive Principle:
Principle #15Dynamics

2Loss of time

If specimen containers are evenly distributed across multiple detection apparatuses, then processing time is reduced, but temperature variations increase

Engineering Contradiction:
Improveprocessing timeVSAvoidtemperature stability
Core Design Contradiction:
Loss of timeVSTemperature

Solution Approach 1:

The system applies different distribution strategies to different detection apparatuses based on their local conditions. Instead of uniform distribution, each apparatus receives containers according to its specific loading capacity, temperature stability, and processing speed, allowing optimized performance for each local context while maintaining overall system efficiency.

Inventive Principle:
Principle #3Local quality

3Productivity

If more specimen containers are processed simultaneously, then throughput is improved, but the accuracy of microbial growth detection decreases

Engineering Contradiction:
ImprovethroughputVSAvoiddetection accuracy
Core Design Contradiction:
ProductivityVSMeasurement precision

Solution Approach 1:

The system monitors detection accuracy metrics and processing load in real-time, using this feedback to adjust the distribution of specimen containers. When detection accuracy begins to degrade due to excessive loading, the system automatically redistributes containers to maintain optimal detection conditions while preserving as much throughput as possible.

Inventive Principle:
Principle #23Feedback

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

This approach enhances the overall efficiency of microbial detection by optimizing the distribution of specimen containers, reducing temperature variations, and improving the throughput of the detection process, thereby facilitating faster and more accurate identification of microbial agents.

Implementation Method 1

an optical detection unit in the incubator analyzes a colorimetric sensor incorporated into the bottle to detect whether microbial growth has occurred within the bottle

Methodology Applied
Scientific EffectOptical absorption: Absorption (EM radiation)

Implementation Method 2

one or more heating means to provide a heated enclosure or incubation chamber

Methodology Applied
Scientific EffectHeating: Heating

Data Source

PatentUS11625025B2System and method of load balancing specimen containers within detection instruments
Publication Date: 2023.04.11 BIOMERIEUX INC
  • US11625025B2 patent drawing
  • US11625025B2 patent drawing
  • US11625025B2 patent drawing

AI summary

The present invention is directed to a system and method for load balancing specimen containers between a plurality of automated detection apparatuses. The method may include receiving a specimen container at a container pick-up station in a first automated detection apparatus; determining loading ability, transfer status, and cell availability of the first automated detection apparatus and one or more downstream automated detection apparatuses; and transferring the specimen container from the first automated detection apparatus to a downstream automated detection apparatus when a first ratio of effective available cell count to effective capacity in the first automated detection apparatus is less than a second ratio of total effective available cell count to total effective capacity of a sum of the first automated detection apparatus and the one or more downstream automated detection apparatuses.