Speckle-Based Distortion Correction in Laser Scanning Microscopy

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Solution Overview

Problem

Image distortion caused by non-uniform laser scanning in devices like catheter and capsule endoscopy due to friction variations during rotation, leading to geometric distortions in image data.

Innovation Solution

Utilizing speckle artifacts from laser illumination to measure and correct image distortion by analyzing speckle shape and size, applying high-pass filtering, and adjusting image dimensions based on aspect ratios to align features, thereby compensating for nonlinear motion-related distortions.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Ease of operation

If non-uniform laser scanning is performed due to friction variations, then the imaging device can rotate and scan, but geometric distortions are introduced in the image data

Engineering Contradiction:
Improverotation and scanning capabilityVSAvoidgeometric accuracy of image data
Core Design Contradiction:
Ease of operationVSManufacturing precision

Solution Approach 1:

The patent uses the speckle artifacts, which are normally considered harmful noise in laser imaging, as beneficial reference features for measuring and correcting the geometric distortions caused by non-uniform scanning. By analyzing the shape and size changes of speckles, the system can quantify the distortion and apply corrections to restore geometric accuracy.

Inventive Principle:
Principle #22Blessing in disguise (Convert harm into benefit)

2Adaptability or versatility

If friction varies during rotation depending on orientation and waveform, then the scanning can adapt to different positions, but the distortion becomes unknown and unpredictable

Engineering Contradiction:
Improvescanning at different orientationsVSAvoiddistortion measurement accuracy
Core Design Contradiction:
Adaptability or versatilityVSMeasurement precision

Solution Approach 1:

The system implements a feedback mechanism where speckle measurements from the image data are continuously used to measure and quantify the actual scanning distortions. This measured distortion information is then fed back to correct the image data, creating a closed-loop system that compensates for friction-induced variations in real-time.

Inventive Principle:
Principle #23Feedback

Solution Approach 2:

The imaging device uses its own speckle artifacts, which are inherently present in the captured images, as the reference standard for self-diagnosis and self-correction of scanning distortions. No external calibration targets or additional reference systems are needed—the system serves itself by utilizing the natural speckle pattern in the image data.

Inventive Principle:
Principle #25Self-service

3Device complexity

If software-based correction techniques are used, then the system becomes simpler and more cost-effective, but complex image processing is required

Engineering Contradiction:
Improvehardware complexityVSAvoidimage processing complexity
Core Design Contradiction:
Device complexityVSDifficulty of detecting and measuring

Solution Approach 1:

The patent replaces complex hardware-based distortion correction mechanisms with software-based image processing. Instead of using additional sensors, motors, or mechanical calibration systems, the invention uses computational algorithms to analyze speckle patterns and correct geometric distortions, thereby reducing hardware complexity while managing software processing requirements.

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

Enhances image accuracy and robustness by correcting distortions in real-time or post-processing, resulting in clearer and more reliable imaging outcomes.

Implementation Method 1

a coherent light source... a laser source that illuminates a sample

Methodology Applied
Scientific EffectLaser: Laser

Implementation Method 2

an image recorder that records properties of light that is reflected from or transmitted through the sample

Methodology Applied
Scientific EffectLight detection: Photoelectric Effect

Data Source

PatentUS12495972B2Speckle-based image distortion correction for laser scanning microscopy
Publication Date: 2025.12.16 THE GENERAL HOSPITAL CORP
  • US12495972B2 patent drawing
  • US12495972B2 patent drawing
  • US12495972B2 patent drawing

AI summary

A method of correcting distortion of an image, including: analyzing, by a processor, an image segment of the image to identify a speckle artifact, the image segment being obtained from a scanning imaging device; determining, by the processor, an aspect ratio of a shape of the speckle artifact; determining, by the processor, a correction factor for the shape of the speckle artifact based on the aspect ratio; and adjusting, by the processor, a dimension of the image segment based on the correction factor.