Speckle Tissue Imaging Brightness Calibration Across Exposure Times

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Solution Overview

Problem

The multi-exposure imaging technique for speckle pattern-based functional imaging is hindered by the difficulty in frequent calibration due to time-consuming processes for minimizing brightness and noise level deviations between images.

Innovation Solution

A device and method that utilize incoherent and coherent light sources to irradiate tissue, adjust light quantity, and control image acquisition to ensure images with varying exposure times have consistent brightness values, using a control unit to derive correlations and set appropriate light quantities for each exposure time.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Measurement precision

If multi-exposure imaging technique is used for speckle pattern-based functional imaging, then functional image quality is improved, but calibration time increases significantly

Engineering Contradiction:
Improvefunctional image qualityVSAvoidcalibration time
Core Design Contradiction:
Measurement precisionVSLoss of time

Solution Approach 1:

The patent performs brightness calibration in advance by capturing a calibration image before functional imaging, pre-determining the relationship between exposure time and brightness values. This preliminary calibration data is stored and reused for subsequent functional imaging sessions, eliminating the need for repeated time-consuming calibration processes while maintaining image quality consistency.

Inventive Principle:
Principle #10Preliminary action

Solution Approach 2:

The patent creates a brightness calibration model by capturing calibration images at multiple exposure times and fitting a curve to establish the relationship between exposure time and brightness. This calibrated brightness characteristic is then copied and applied to correct functional images acquired at different exposure times, avoiding direct repeated calibration while preserving measurement precision.

Inventive Principle:
Principle #26Copying

2Adaptability or versatility

If multiple images with different exposure times are acquired, then functional imaging capability is enhanced, but brightness consistency between images deteriorates

Engineering Contradiction:
Improvefunctional imaging capabilityVSAvoidbrightness consistency
Core Design Contradiction:
Adaptability or versatilityVSStability of the object's composition

Solution Approach 1:

The patent establishes a feedback mechanism where calibration images are captured to determine the actual brightness characteristics of the imaging system. The derived brightness correction factors are then applied to functional images to compensate for exposure time variations, creating a closed-loop system that maintains brightness consistency across multi-exposure functional imaging sequences.

Inventive Principle:
Principle #23Feedback

Solution Approach 2:

The patent systematically varies exposure time parameters across multiple images to enhance functional imaging capability, while simultaneously applying brightness correction based on calibration data to maintain brightness consistency. The calibration process establishes the parameter relationship between exposure time and brightness, enabling corrected multi-parameter imaging.

Inventive Principle:
Principle #35Parameter changes

3Measurement precision

If calibration process is performed to minimize brightness deviations, then image accuracy is improved, but operational complexity increases

Engineering Contradiction:
Improveimage accuracyVSAvoidoperational complexity
Core Design Contradiction:
Measurement precisionVSEase of operation

Solution Approach 1:

The patent implements a self-calibrating system where the imaging device automatically captures calibration images and computes brightness correction factors without requiring manual intervention. The calibration process is integrated into the imaging workflow, and the system autonomously applies corrections to functional images, reducing operational complexity while maintaining high image accuracy.

Inventive Principle:
Principle #25Self-service

Solution Approach 2:

The calibration process is performed once in advance to establish brightness characteristics, and this preliminary calibration data is stored for reuse. This eliminates the need for repeated manual calibration operations, significantly reducing operational complexity while maintaining measurement precision across multiple imaging sessions.

Inventive Principle:
Principle #10Preliminary action

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

Enables quick and accurate calibration, allowing for high-resolution functional imaging in applications like lesion diagnosis and surgical monitoring, contributing to precise diagnostic and procedural accuracy.

Implementation Method 1

an image (or an image having a speckle pattern in the case of the coherent light source) formed as light emitted from the light source is scattered in the tissue

Methodology Applied
Scientific EffectSpeckle pattern: Interference

Implementation Method 2

an image (or an image having a speckle pattern in the case of the coherent light source) formed as light emitted from the light source is scattered in the tissue

Methodology Applied
Scientific EffectLight scattering: Scattering

Data Source

PatentUS12490902B2Device for acquiring functional image of tissue and method for generating same
Publication Date: 2025.12.09 R GEN VISION INC
  • US12490902B2 patent drawing
  • US12490902B2 patent drawing
  • US12490902B2 patent drawing

AI summary

The present invention discloses a device for acquiring a functional image of tissue and a method for acquiring a functional image by using same, the device comprising: a light source for irradiating a tissue to be imaged with coherent light; an image acquisition unit for acquiring an image of a speckle pattern which is formed by scattering the light emitted from the light source over the tissue, and acquiring multiple images having different exposure times; an image processing unit for generating a functional image of the tissue on the basis of the multiple images acquired by the image acquisition unit; and a control unit for adjusting the light quantity of the light emitted to the tissue such that the multiple images having different exposure times have brightness values in a common range, and controlling the operation of the image acquisition unit.