Spectral Data Condensing for Real-Time Microanalysis

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Solution Overview

Problem

Spectral microanalysis is time-consuming due to the need for extensive data collection and analysis of hyperspectral data cubes, particularly when dealing with large specimen areas and complex compositions, as existing methods require scanning and statistical processing that can take minutes to hours even with fast computers.

Innovation Solution

The method involves condensing spectral data by combining emission counts in adjacent energy intervals and spatially combining pixel spectra during data collection, allowing for preliminary analysis results to be provided in real-time, with the option to gradually increase resolution as more data is collected, significantly reducing processing time.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Measurement precision

If spectra are collected from multiple pixels across a specimen region using an excitation beam scan, then spatial composition information is obtained, but data collection and analysis time increases significantly

Engineering Contradiction:
Improvespatial composition informationVSAvoiddata collection and analysis time
Core Design Contradiction:
Measurement precisionVSLoss of time

Solution Approach 1:

The patent performs preliminary statistical analysis during the data collection phase rather than after complete data acquisition. By analyzing spectra as they are being collected from multiple pixels, the system provides preliminary composition information before the full hyperspectral data cube is complete, thereby reducing the perceived analysis time while maintaining measurement precision.

Inventive Principle:
Principle #10Preliminary action

Solution Approach 2:

The patent divides the analysis process into segments that can be performed independently and in parallel. By collecting and analyzing spectra from different pixel regions simultaneously or in overlapping time periods, the system processes spatial composition data in manageable segments rather than treating the entire dataset as a single analysis unit, thus reducing overall processing time.

Inventive Principle:
Principle #1Segmentation

2Measurement precision

If statistical analysis is performed on complete hyperspectral data cubes, then accurate component identification is achieved, but processing time extends to minutes or hours

Engineering Contradiction:
Improvecomponent identification accuracyVSAvoidanalysis throughput
Core Design Contradiction:
Measurement precisionVSProductivity

Solution Approach 1:

The patent performs preliminary statistical analysis during the data collection phase rather than after complete data acquisition. By analyzing spectra as they are being collected from multiple pixels, the system provides preliminary composition information before the full hyperspectral data cube is complete, thereby reducing the perceived analysis time while maintaining measurement precision.

Inventive Principle:
Principle #10Preliminary action

Solution Approach 2:

The patent accepts that preliminary analysis results may be based on incomplete data (partial action) rather than waiting for complete data acquisition. The system provides useful composition information from the portion of data that has been collected and analyzed so far, enabling faster turnover with the understanding that results may be refined as additional data is processed.

Inventive Principle:
Principle #16Partial or excessive action

3Measurement precision

If spectra from multiple pixels are analyzed to determine specimen composition, then comprehensive material characterization is obtained, but data volume and analysis complexity increase

Engineering Contradiction:
Improvematerial characterization completenessVSAvoiddata processing complexity
Core Design Contradiction:
Measurement precisionVSDevice complexity

Solution Approach 1:

The patent divides the analysis process into segments that can be performed independently and in parallel. By collecting and analyzing spectra from different pixel regions simultaneously or in overlapping time periods, the system processes spatial composition data in manageable segments rather than treating the entire dataset as a single analysis unit, thus reducing overall processing complexity.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The patent performs preliminary statistical analysis during the data collection phase rather than after complete data acquisition. By analyzing spectra as they are being collected from multiple pixels, the system provides preliminary composition information before the full hyperspectral data cube is complete, thereby reducing the perceived analysis time while maintaining measurement precision.

Inventive Principle:
Principle #10Preliminary action

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

This approach reduces analysis time from minutes to seconds, enabling analysts to receive preliminary results promptly and update them as data is collected, enhancing productivity and accuracy without significantly degrading component identification.

Implementation Method 1

directing an excitation beam - such as an electron beam or X-ray beam - at a specimen, and then capturing and analyzing the radiation and/or particles emitted by the specimen in response to the excitation beam

Methodology Applied
Scientific EffectX-ray emission: X-Ray

Implementation Method 2

directing an excitation beam - such as an electron beam or X-ray beam - at a specimen

Methodology Applied
Scientific EffectElectron beam interaction: Electron Beam

Data Source

PatentEP2047245B1Automatic material labeling during spectral image data acquisition
Publication Date: 2022.09.21 THERMO ELECTRONICS SCI INSTR LLC
  • EP2047245B1 patent drawingFigure 1
  • EP2047245B1 patent drawingFigure 2~3C
  • EP2047245B1 patent drawingFigure 4A~4C

AI summary

A system for performing spectral microanalysis delivers analysis results during the course of data collection As spectra are collected from pixels on a specimen, the system periodically analyzes the spectra to statistically derive underlying spectra representing proposed specimen components(A), wherein the derived spectra combine in varying proportions to result (at least approximately) in the measured spectra at each pixel Those pixels having the same dominant proposed component, and/or which contain at least approximately the same proportions of the proposed components, may then have their measured spectra combined (i e, added or averaged) (C, D) These spectra may then be cross-referenced via reference libraries to identify the components actually present(E) During the foregoing analysis, the measured spectra are preferably condensed, as by reducing the number of energy channels /intervals making up the measured spectra and/or by combining the measured spectra of adjacent pixels, to reduce the size of the data cube and expedite analysis results (G).