Spectral Wavefront Analysis for Ocular Metrology

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Solution Overview

Problem

Current metrology techniques for the human eye, such as hyperspectral imaging and wavefront analysis, face challenges in maintaining accurate relative phase information between sampling points and wavelengths, especially due to motion artefacts and the difficulty in achieving high accuracy in three-dimensional scans.

Innovation Solution

A spectral wavefront analyser system that uses a two-dimensional sampling array with micro lens arrays to extract optical phase and spectral information from multiple sampling points in a single acquisition, employing dispersive elements like gratings and polarisation optics to reduce motion artefacts and provide balanced detection, enabling accurate tomographic profiling of the eye's anterior segment.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Measurement precision

If traditional scanning-based wavefront analysis is used, then detailed optical phase information can be obtained, but motion artefacts increase and measurement time increases

Engineering Contradiction:
Improveoptical phase information accuracyVSAvoidmeasurement time
Core Design Contradiction:
Measurement precisionVSLoss of time

Solution Approach 1:

The wavefront is segmented into multiple discrete sampling points arranged in a two-dimensional array, allowing simultaneous measurement of optical phase at each point through the interferometric system, thereby eliminating the need for sequential scanning and reducing motion artefacts

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The measurement approach transitions from one-dimensional sequential scanning to two-dimensional parallel sampling, where multiple beamlets illuminate different spatial points simultaneously and the interferometric detector captures phase information across the entire wavefront in a single acquisition

Inventive Principle:
Principle #17Another dimension (Dimensionality change)

2Loss of information

If hyperspectral imaging is used to gather intensity information, then spectral features can be analysed, but phase information is lost

Engineering Contradiction:
Improvephase information retentionVSAvoidsystem complexity
Core Design Contradiction:
Loss of informationVSDevice complexity

Solution Approach 1:

The system merges interferometric wavefront sensing with spectral imaging by combining a beam splitter, dispersive element, and two-dimensional detector array, enabling simultaneous capture of both intensity and phase information across multiple wavelengths in a single measurement

Inventive Principle:
Principle #5Merging (Combining)

Solution Approach 2:

The interferometric spectral imaging system serves multiple functions: it performs wavefront analysis, spectral analysis, and tomographic profiling simultaneously, eliminating the need for separate measurement systems and reducing overall device complexity

Inventive Principle:
Principle #6Universality (Multi-functionality)

3Measurement precision

If multi-wavelength wavefront analysis is performed, then dispersive properties can be measured, but relative phase information between wavelengths is not obtained

Engineering Contradiction:
Improverelative phase information accuracyVSAvoidmeasurement difficulty
Core Design Contradiction:
Measurement precisionVSDifficulty of detecting and measuring

Solution Approach 1:

A dispersive element acts as an intermediary that spatially separates different wavelengths in the spectral direction while the interferometric setup maintains phase coherence across wavelengths, allowing the detector to capture relative phase information between different spectral components

Inventive Principle:
Principle #24Intermediary (Mediator)

Solution Approach 2:

The system replaces complex mechanical phase-shifting equipment with a stationary interferometric arrangement combined with spectral dispersion, using optical field interference patterns to encode phase information that can be decoded through computational algorithms

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

This approach allows for precise measurement of optical phase and spectral information across a multi-wavelength wavefront, reducing motion artefacts and enabling high-resolution, single-shot acquisitions of ocular data, including corneal topography and wavefront analysis, with improved accuracy and reduced clinical complexity.

Implementation Method 1

an interferometric arrangement in which an incoming known multi-wavelength wavefront is divided by a beam splitter into reference and probe beams

Methodology Applied
Scientific EffectInterference: Interference

Implementation Method 2

A dispersive element such as a grating 225 which angularly disperses the wavelength components of the light

Methodology Applied
Scientific EffectDiffraction: Diffraction

Implementation Method 3

A spectral wavefront analyser system that uses a two-dimensional sampling array with micro lens arrays

Methodology Applied
Scientific EffectFocusing: Focusing

Implementation Method 4

extract optical phase and spectral information from multiple sampling points in a single acquisition, employing dispersive elements like gratings and polarisation optics

Methodology Applied
Scientific EffectInterference: Interference

Data Source

PatentEP3011288B1Ocular metrology employing spectral wavefront analysis of reflected light
Publication Date: 2020.12.23 CYLITE
  • EP3011288B1 patent drawingFigure 1
  • EP3011288B1 patent drawingFigure 2
  • EP3011288B1 patent drawingFigure 3~3a

AI summary

Method and systems are presented for analysing a wavefront using a spectral wavefront analyser to extract optical phase and spectral information at a two dimensional array of sampling points across the wavefront, wherein the relative phase information between the sampling points is maintained. Methods and systems are also presented for measuring an eye by reflecting a wavefront of an eye and measuring the wavefront at a plurality of angles to provide a map of the off-axis relative wavefront curvature and aberration of the eye. The phase accuracy between wavelengths and sample points over a beam aperture offered by these methods and systems have a number of ocular applications including corneal and anterior eye tomography, high resolution retinal imaging, and wavefront analysis as a function of probe beam incident angle for determining myopia progression and for designing and testing lenses for correcting myopia.