Mass Spectrometer Maintenance Prediction With Hardware Pre-Adjustment

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Solution Overview

Problem

Existing maintenance techniques for scientific instruments, such as chromatograph-equipped mass spectrometers, rely on manual scheduling, leading to potential delays or neglect of maintenance tasks, which can result in instrument degradation.

Innovation Solution

A computer-implemented method and system that integrates a determination component, scheduling component, and preparation component to automatically assess the need for maintenance, predict a suitable time for maintenance based on operational history and metadata, and adjust hardware settings in preparation for the maintenance task.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If manual maintenance scheduling is used, then device complexity is reduced, but maintenance timeliness and instrument reliability deteriorate

Engineering Contradiction:
Improveinstrument reliabilityVSAvoidmaintenance system complexity
Core Design Contradiction:
ReliabilityVSDevice complexity

Solution Approach 1:

The scientific instrument performs self-diagnosis by automatically monitoring its own operational parameters and maintenance status. The determination component resides within the instrument itself, enabling it to autonomously identify when maintenance is needed without external intervention, thereby improving reliability while avoiding complex external monitoring systems.

Inventive Principle:
Principle #25Self-service

Solution Approach 2:

The system implements a feedback loop where the determination component continuously monitors instrument status, compares it against predefined thresholds, and triggers maintenance scheduling when degradation is detected. This closed-loop feedback mechanism ensures timely maintenance while keeping the system architecture relatively simple.

Inventive Principle:
Principle #23Feedback

2Loss of time

If automated maintenance determination is implemented, then maintenance timeliness improves, but device complexity increases

Engineering Contradiction:
Improvemaintenance delay timeVSAvoidmaintenance system complexity
Core Design Contradiction:
Loss of timeVSDevice complexity

Solution Approach 1:

The determination component proactively assesses maintenance needs before actual degradation occurs by continuously monitoring operational parameters. The scheduling component then preliminarily schedules maintenance tasks in advance, eliminating delays while avoiding the complexity of real-time emergency response systems.

Inventive Principle:
Principle #10Preliminary action

Solution Approach 2:

The patent replaces manual mechanical scheduling with automated electronic determination and scheduling components. This substitution uses software-based logic instead of physical scheduling mechanisms, reducing maintenance delay while the modular component architecture keeps overall system complexity manageable.

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

3Productivity

If hardware actuators are adjusted in preparation for maintenance, then maintenance efficiency improves, but device complexity increases

Engineering Contradiction:
Improvemaintenance efficiencyVSAvoidhardware control complexity
Core Design Contradiction:
ProductivityVSDevice complexity

Solution Approach 1:

The scheduling component automatically adjusts hardware actuators to predetermined preparation states before maintenance begins. For example, actuators position components in accessible configurations or prepare fluid systems for drainage, thereby improving maintenance efficiency while using simple pre-programmed positioning logic.

Inventive Principle:
Principle #10Preliminary action

Solution Approach 2:

The system changes hardware parameters (such as actuator positions, valve states, or temperature settings) to optimal values for maintenance operations. These parameter adjustments are automated but follow predefined maintenance protocols, improving efficiency without requiring complex real-time control algorithms.

Inventive Principle:
Principle #35Parameter changes

Data Source

PatentEP4509830A1Intelligent maintenance for scientific instruments
Publication Date: 2025.02.19 THERMO FINNIGAN LLC
  • EP4509830A1 patent drawingFigure 1
  • EP4509830A1 patent drawingFigure 2
  • EP4509830A1 patent drawingFigure 3

AI summary

Systems or techniques are provided for facilitating intelligent maintenance for scientific instruments. In various embodiments, a scientific instrument can comprise a chromatograph-equipped mass spectrometer. In various aspects, the scientific instrument can determine, based on an electronic counter or readback sensor associated with the chromatograph-equipped mass spectrometer failing to satisfy a threshold, whether performance of a maintenance task on the chromatograph-equipped mass spectrometer is warranted. In various instances, the scientific instrument can schedule, in response to a determination that the performance of the maintenance task is warranted, a time or date for the performance of the maintenance task, wherein the time or date can be predicted by a machine learning model based on an operational history of the chromatograph-equipped mass spectrometer. In various cases, the scientific instrument can prepare for the performance of the maintenance task, by adjusting, prior to the time or date, actuatable hardware of the chromatograph-equipped mass spectrometer.