Spectroscopic Measurement Device Light Efficiency Biomembrane Analysis

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Solution Overview

Problem

Conventional spectroscopic measurement devices are not suitable for non-invasive, portable, and efficient analysis of biomembranes due to low light efficiency and difficulty in measuring weak light scattered inside biomembranes, especially when the measurement object moves, such as during breathing or heartbeats.

Innovation Solution

A spectroscopic measurement device and method utilizing a division optical system to join and divide light rays from a measurement point into two beams, an imaging optical system to focus these beams on a single line, an optical path length difference changer to alter the path difference between the beams, and a detection unit to obtain an interferogram and Fourier-convert it for spectral analysis, enhancing light efficiency and reducing the need for mechanical scanning.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Measurement precision

If a pinhole or slit is used to enhance spatial coherency of object lights in conventional spectroscopic techniques, then spectral measurement capability is improved, but light efficiency deteriorates because most object light does not pass through the pinhole or slit

Engineering Contradiction:
Improvespectral measurement capabilityVSAvoidlight efficiency
Core Design Contradiction:
Measurement precisionVSLoss of energy

Solution Approach 1:

The patent replaces the mechanical pinhole/slit spatial filtering system with a computational approach. By capturing scattered light from multiple positions using an imaging device and processing the light intensity distributions computationally, the system achieves spectral measurement capability without the light loss inherent in physical pinhole or slit methods.

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

Solution Approach 2:

The imaging device serves multiple functions: it captures scattered light from arbitrary positions within the biomembrane, records light intensity distributions, and enables spectral characteristic evaluation through computational processing. This multi-functional approach eliminates the need for specialized pinhole or slit components while maintaining measurement capability.

Inventive Principle:
Principle #6Universality (Multi-functionality)

2Measurement precision

If conventional spectroscopic techniques are used to measure spectral characteristics, then spectral analysis capability is achieved, but measurement of weak scattered light inside biomembranes becomes difficult due to low light efficiency

Engineering Contradiction:
Improvespectral analysis capabilityVSAvoidweak light measurement capability
Core Design Contradiction:
Measurement precisionVSDifficulty of detecting and measuring

Solution Approach 1:

The patent replaces conventional optical filtering mechanisms with computational processing of light intensity distributions captured by an imaging device. This substitution enables efficient capture and analysis of weak scattered light from biomembranes without the light loss associated with traditional pinhole or slit methods.

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

Solution Approach 2:

The system captures light intensity distributions from multiple positions within the biomembrane and creates computational representations of these distributions. By processing these copied light intensity patterns, the system can evaluate spectral characteristics of weak scattered light that would be insufficient for conventional measurement methods.

Inventive Principle:
Principle #26Copying

3Ease of operation

If the measurement object moves due to breathing and heartbeats, then non-invasive measurement of living biomembranes is achieved, but spectral measurement accuracy deteriorates

Engineering Contradiction:
Improvenon-invasive measurement capabilityVSAvoidspectral measurement accuracy
Core Design Contradiction:
Ease of operationVSMeasurement precision

Solution Approach 1:

The patent captures light intensity distributions at multiple time points, effectively sampling the moving biomembrane at periodic intervals. By processing these temporally separated measurements, the system can extract spectral characteristics despite the periodic movements caused by breathing and heartbeats.

Inventive Principle:
Principle #19Periodic action

Solution Approach 2:

The imaging device captures both spatial and temporal information in a single measurement system. By recording light intensity distributions across multiple positions and time points, the system simultaneously achieves non-invasive measurement capability and maintains spectral accuracy despite biomembrane movement.

Inventive Principle:
Principle #6Universality (Multi-functionality)

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The solution provides high light efficiency for weak light measurements, reduces measurement time, and allows for a compact, portable device capable of accurate spectral analysis of biomembranes with improved spatial and temporal resolution.

Implementation Method 1

utilizing a division optical system to join and divide light rays from a measurement point into two beams... an optical path length difference changer to alter the path difference between the beams... a detection unit to obtain an interferogram

Methodology Applied
Scientific EffectInterference: Interference

Implementation Method 2

an imaging optical system to focus these beams on a single line

Methodology Applied
Scientific EffectFocusing: Focusing

Implementation Method 3

an optical path length difference changer to alter the path difference between the beams

Methodology Applied
Scientific EffectOptical path difference:

Implementation Method 4

a detection unit to obtain an interferogram and Fourier-convert it for spectral analysis

Methodology Applied
Scientific EffectFourier transformation:

Data Source

PatentUS8988689B2Spectroscopic measurement device and spectroscopic measurement method
Publication Date: 2015.03.24 KAGAWA UNIVERSITY
  • US8988689B2 patent drawing
  • US8988689B2 patent drawing
  • US8988689B2 patent drawing

AI summary

Multiple rays such as scattered lights and fluorescent lights emitted radially in a variety of directions from each bright point in a measurement area enter an objective lens, where the multiple rays are converted into a parallel beam. The parallel beam is reflected by both a reference mirror unit and an oblique mirror unit, and the reflected beams pass through an imaging lens to form an interference image on a light-receiving surface of a detection unit. The detection of the light intensity of the interference image on the light-receiving surface enables an acquisition of the interferogram (the waveform of the change of imaging intensity) in which the light intensity continuously changes. By Fourier-converting the interferogram, spectral characteristics can be obtained which show the relative intensities for each wavelength of the lights emitted from one bright point of an object to be measured.