Speech Analysis Ensemble Classifier for Cognitive Decline Detection

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Solution Overview

Problem

Current methods lack an effective way to detect cognitive decline in individuals, particularly in the early stages of Mild Cognitive Impairment (MCI), which can precede Alzheimer's disease or other dementias.

Innovation Solution

A system and method that utilize speech data analysis by obtaining baseline and trial speech data from subjects, extracting features, normalizing the trial data, and using a trained ensemble classifier to identify whether the subject's speech patterns indicate normal cognitive function or cognitive decline.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Measurement precision

If speech data analysis is used to detect cognitive decline, then early detection capability is improved, but system complexity increases due to multiple classifiers and feature extraction steps

Engineering Contradiction:
Improvedetection accuracyVSAvoidsystem complexity
Core Design Contradiction:
Measurement precisionVSDevice complexity

Solution Approach 1:

The system segments the detection task into multiple independent component classifiers, each analyzing specific speech features. These component classifiers are then combined through an ensemble module to produce the final detection result. This segmentation allows each classifier to specialize in particular aspects of speech analysis, improving overall detection accuracy while maintaining manageable complexity through modular design.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The ensemble classifier system serves multiple functions: it performs feature extraction from raw speech data, normalizes data across different subjects, applies multiple classification algorithms simultaneously, and integrates results through ensemble methods. This multi-functionality consolidates what would otherwise require separate systems into a unified platform, improving detection capability without proportionally increasing system complexity.

Inventive Principle:
Principle #6Universality (Multi-functionality)

2Reliability

If multiple component classifiers are used to analyze different feature subsets, then detection reliability is improved, but processing time increases

Engineering Contradiction:
Improvedetection reliabilityVSAvoidprocessing time
Core Design Contradiction:
ReliabilityVSLoss of time

Solution Approach 1:

Each component classifier analyzes only a subset of features rather than the complete feature set, performing partial analysis that is sufficient for its specific classification task. The ensemble module then integrates these partial results to achieve comprehensive detection. This partial action approach reduces the computational burden on each individual classifier while maintaining overall detection reliability through the collective contribution of multiple specialized classifiers.

Inventive Principle:
Principle #16Partial or excessive action

Solution Approach 2:

The system performs self-optimization by automatically selecting and training component classifiers that are best suited for specific feature subsets. The ensemble module self-adjusts by weighting and combining classifier outputs based on their individual performance characteristics. This self-service capability allows the system to achieve high reliability without manual intervention to balance the number of classifiers against processing time requirements.

Inventive Principle:
Principle #25Self-service

3Measurement precision

If baseline speech data is collected multiple times for normalization, then measurement precision is improved, but data collection time increases

Engineering Contradiction:
Improvenormalization accuracyVSAvoiddata collection time
Core Design Contradiction:
Measurement precisionVSLoss of time

Solution Approach 1:

The system collects baseline speech data multiple times before the actual trial recordings to establish a comprehensive reference profile for each subject. This preliminary data collection creates a robust baseline that captures the subject's natural speech variations. By performing this normalization reference collection in advance, the system enables rapid normalization during trial analysis without requiring repeated baseline collections, thus improving measurement precision while managing data collection time efficiently.

Inventive Principle:
Principle #10Preliminary action

Data Source

PatentUS12277929B2System and method for detecting cognitive decline using speech analysis
Publication Date: 2025.04.15 JANSSEN PHARMA NV
  • US12277929B2 patent drawing
  • US12277929B2 patent drawing
  • US12277929B2 patent drawing

AI summary

System and method for detecting cognitive decline in a subject using a classification system for detecting cognitive decline in the subject based on a speech sample. The classification system is trained using speech data corresponding to audio recordings of speech from normal and cognitive decline patients to generate an ensemble classifier comprising a plurality of component classifiers and an ensemble module. Each of the plurality of component classifiers is a machine-learning classifier configured to generate a component output identifying a sample data as corresponding to a normal patient or a cognitive patient. The machine-learning classifier is generated based on a subset of available features. The ensemble module receives component outputs from all of the component classifiers and generates an ensemble output identifying the sample data as corresponding to a normal or cognitive decline patient based on the component outputs.