Sperm Motility Enhancement via 390-420 nm Light Irradiation

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Solution Overview

Problem

Current methods for increasing sperm motility in animals, such as those used in artificial insemination, face challenges including the use of chemical agents that raise safety concerns and are costly, and existing light-based methods do not efficiently enhance motility beyond 50%.

Innovation Solution

Irradiating spermatozoa with light in the wavelength range of 390-420 nm, specifically at a fluence effective to increase motility by 75% or more, using a method and apparatus that includes a holding unit, a lighting unit capable of emitting light in this range, and a light controller to optimize irradiation parameters.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Speed

If chemical agents are used to activate sperm motility, then sperm motility is improved, but safety concerns and cost increase

Engineering Contradiction:
Improvesperm motilityVSAvoidsafety concerns
Core Design Contradiction:
SpeedVSObject-affected harmful factors

Solution Approach 1:

The patent replaces chemical activation methods with optical irradiation (light at specific wavelengths) to activate sperm motility. This substitution eliminates the need for chemical agents that raise safety concerns, while achieving the desired effect of increased sperm motility through non-invasive light exposure.

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

Solution Approach 2:

The patent changes the physical parameter of light wavelength (specifically using light in the range of approximately 390-420 nm) to achieve sperm activation. By optimizing the wavelength parameter, the method achieves effective motility enhancement without the harmful effects associated with chemical agents.

Inventive Principle:
Principle #35Parameter changes

2Speed

If existing light-based methods are used to increase sperm motility, then some improvement is achieved, but the increase is limited to about 50%

Engineering Contradiction:
Improvesperm motilityVSAvoidmotility enhancement efficiency
Core Design Contradiction:
SpeedVSProductivity

Solution Approach 1:

The patent optimizes the light wavelength parameter to approximately 390-420 nm, which represents a specific refinement in the spectral range. This parameter optimization enables the method to achieve over 75% motility enhancement, significantly improving upon previous methods that were limited to about 50% enhancement.

Inventive Principle:
Principle #35Parameter changes

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

This approach significantly increases sperm motility by 75% or more, as demonstrated by increased parameters like average path velocity, providing a more efficient and safer method compared to chemical agents and previous light-based techniques.

Implementation Method 1

irradiating the spermatozoa with light having wavelengths in a range of 390-420 nm at a fluence effective to increase the motility of the spermatozoa by 75% or more

Methodology Applied
Scientific EffectPhotonic effect: Light

Data Source

PatentUS20240238075A1Method and apparatus for increasing sperm motility
Publication Date: 2024.07.18 NICHIA CORP
  • US20240238075A1 patent drawing
  • US20240238075A1 patent drawing
  • US20240238075A1 patent drawing

AI summary

An apparatus for treating spermatozoa of an animal to increase motility includes: a holding or mounting unit configured to hold or support a sperm container; a lighting unit configured to irradiate the sperm container held or supported by the holding or mounting unit with light having wavelengths in a range of 390-420 nm; and a light controller unit configured to control the lighting unit.