Spherical Cosmetic Particles Stabilizing Oxidation-Sensitive Actives
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Solution Overview
Problem
Current cosmetic and dermatological preparations face challenges in stabilizing oxidation-sensitive and UV-sensitive active ingredients, leading to limited effectiveness and potential skin irritation, particularly in addressing skin aging and photodermatoses, with existing antioxidants like vitamin E falling short in providing long-term protection against oxidative and UV-induced damage.
Innovation Solution
The development of cosmetic preparations containing ubiquinones and plastoquinones, combined with metal oxide pigments and light filter substances, encapsulated in a polymer matrix within spherical particles, which are protected against oxygen and UV radiation, maintaining their effectiveness over time and providing comprehensive skin care and light protection.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Reliability
If oxidation-sensitive and UV-sensitive active ingredients are used in cosmetic preparations, then effectiveness in protecting against skin aging and photodermatoses is improved, but stability of the active ingredients deteriorates due to oxidation and UV degradation
Solution Approach 1:
The preparation is divided into an outer aqueous gel phase and an inner oily phase containing the active ingredients. This segmentation isolates the oxidation-sensitive and UV-sensitive active ingredients within the inner phase, protecting them from direct exposure to oxygen and UV radiation in the outer phase, thereby maintaining both effectiveness and stability.
Solution Approach 2:
The inner oily phase containing the active ingredients is nested within the outer aqueous gel phase. This nested structure provides an additional protective barrier, allowing the active ingredients to be encapsulated and protected from environmental factors while remaining accessible for skin absorption, thus resolving the contradiction between effectiveness and stability.
2Reliability
If antioxidants like vitamin E are used to protect against oxidative damage, then protection effectiveness is improved, but long-term stability against oxidation deteriorates
Solution Approach 1:
The invention changes the physical and chemical parameters of the preparation system by creating a two-phase structure with different oxidation potentials. The inner oily phase acts as an oxidation-resistant compartment, extending the duration of action and long-term stability of the antioxidant active ingredients while maintaining their protection effectiveness.
3Reliability
If light filter substances are added to protect against UV radiation, then light protection effectiveness is improved, but complexity of the formulation increases
Solution Approach 1:
The outer aqueous gel phase serves multiple functions: it acts as a vehicle for the preparation, provides a protective barrier against UV radiation, and maintains the stability of the inner phase. This multi-functionality reduces the need for additional separate light filter substances, thereby maintaining light protection effectiveness while minimizing formulation complexity.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
These preparations effectively stabilize active ingredients, enhancing their longevity and efficacy, offering superior skin care and light protection while preventing oxidative and UV-induced damage, thus addressing the limitations of previous formulations.
Implementation Method 1
one or more light filter substances which is or are selected from the group of metal oxide pigments
Implementation Method 2
essentially spherical particles... which comprise a polymer matrix which is essentially insoluble in water, one or more substances selected from the group of ubiquinones and/or plastoquinones
Data Source
Figure 1a
Figure 1b~1c
Figure 1d
AI summary
Essentially spherical particles whose average diameter is selected from the range of 0.1 to 10 mm, preferably 2 to 7.5 mm, and which comprise: - a polymer matrix which is essentially insoluble in water, - one or more substances selected from the group of ubiquinones and/or plastoquinones, - one or more light filter substances which are or are selected from the group of metal oxide pigments, - optionally one or more light filter substances which are or are selected from the group of conventional cosmetic light protection filter substances.