Spherical Fibrous Therapeutic Material for Intractable Skin Ulcers
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Solution Overview
Problem
Current therapeutic methods are insufficient for treating severe decubitus ulcers, particularly those with pockets or that have progressed to stage III to IV, as they fail to effectively inhibit bacterial infections and promote healing without surgical intervention.
Innovation Solution
A fibrous material, such as cotton, is formed into a spherical shape and impregnated with fradiomycin sulfate for antibacterial action and trafermin for cell proliferation acceleration, allowing for prolonged contact with the ulcer's inner surface to treat decubitus ulcers effectively.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Reliability
If conventional therapeutic methods (ointments, sprays, pastes) are used for severe decubitus ulcers, then the treatment process is simple to apply, but the therapeutic effect is insufficient for intractable ulcers with pockets or stage III-IV ulcers
Solution Approach 1:
The fibrous material is divided into multiple layers with different functions: an outer layer for maintaining moisture and protecting from contamination, and an inner layer containing antibiotic-impregnated fibrous material for direct contact with the ulcer. This segmentation allows each layer to perform its specific function optimally, achieving reliable therapeutic effect while keeping the overall structure manageable
Solution Approach 2:
The invention uses a composite structure combining different types of fibrous materials with distinct properties. The outer layer uses hydrophilic fibrous material for moisture management, while the inner layer uses antibiotic-impregnated fibrous material for infection control. This composite approach achieves superior therapeutic effect by integrating multiple functional materials into a single treatment device
2Area of stationary object
If the therapeutic material is applied to large area ulcers, then the coverage area increases, but the contact time with the inner surface of the ulcer decreases
Solution Approach 1:
The fibrous material is formed into a spherical shape that can conform to the contours of the ulcer cavity. This curved geometry allows the material to nestle into the ulcer pocket, maximizing contact with the inner surface across the entire coverage area. The spherical form maintains stable contact without rolling away, thereby extending the duration of action while covering large ulcer surfaces
3Productivity
If surgical intervention is performed for intractable decubitus ulcers, then the healing speed increases, but the patient's burden and risk increase
Solution Approach 1:
The fibrous material is pre-impregnated with antibiotics and cell proliferation accelerators before application to the ulcer. This preliminary preparation ensures that the therapeutic agents are immediately available upon contact with the ulcer, accelerating the healing process from the outset. The sustained release of these pre-loaded agents maintains high healing speed over an extended period without requiring surgical intervention
Solution Approach 2:
The fibrous material provides continuous therapeutic action through sustained release of antibiotics and cell proliferation accelerators. The material maintains prolonged contact with the ulcer surface, delivering a continuous supply of therapeutic agents that accelerates healing over time. This continuous action achieves high productivity comparable to surgery but without the associated risks and patient burden
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
The therapeutic material effectively treats severe decubitus ulcers by inhibiting bacterial infections and promoting healing, reducing the need for surgical intervention and achieving significant improvement or complete healing of intractable decubitus ulcers.
Implementation Method 1
a fibrous material holding an antibiotic and a cell proliferation accelerator therein
Data Source
AI summary
It is an object to provide a therapeutic material for a skin ulcer which has excellent therapeutic effects on intractable skin ulcers such as decubitus ulcers with pockets and huge decubitus ulcers. By applying the therapeutic material for decubitus ulcers consisting of a fibrous material holding an antibiotic and a cell proliferation accelerator therein which is formed into an approximately spherical shape to a site of decubitus in a state in which a defect extending to the dermis, subcutaneous tissue, muscle or bone occurs, it is possible to treat critical skin ulcers such as intractable decubitus ulcers with pockets and huge intractable decubitus ulcers, as well as to treat not only relatively mild decubitus classified as stage II according to the US National Pressure Ulcer Advisory Panel (NPUAP) staging system, i.e., decubitus having ulcers in a state in which a part of the dermis is deficient, but also severe decubitus that has progressed to stage III to IV according to the NPUAP staging system, particularly decubitus with intractable ulcers with pockets or decubitus with huge intractable ulcers.