Silk protein coatings

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Solution Overview

Problem

Existing methods for modifying inert synthetic or inorganic materials, such as aramid fibers, require harsh conditions like high temperatures and toxic solvents, and fail to provide a pleasant surface feel and efficient molecule attachment.

Innovation Solution

Coating polyaramid materials with spider silk polypeptides under mild conditions, using a solution of spider silk polypeptides and a solvent, allows for stable adherence and improved surface properties.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If common coating methods are used on inert synthetic or inorganic materials, then coating application is possible, but the coating does not stick well and is not durable

Engineering Contradiction:
Improvecoating adhesion and durabilityVSAvoidcoating application process
Core Design Contradiction:
ReliabilityVSEase of manufacture

Solution Approach 1:

The invention changes the chemical parameters of the coating solution by using a basic pH buffer (pH 8-10) to dissolve spider silk proteins, creating a coating that can chemically interact with the inert polyaramid surface. This parameter change enables durable adhesion without requiring harsh application conditions or pre-treatment of the substrate.

Inventive Principle:
Principle #35Parameter changes

Solution Approach 2:

The spider silk protein coating acts as an intermediary layer between the inert polyaramid material and other molecules or surfaces. The protein's amino acid residues provide functional groups that can form chemical bonds, serving as a mediating interface that improves adhesion and enables further molecular attachment on mild conditions.

Inventive Principle:
Principle #24Intermediary (Mediator)

2Reliability

If harsh conditions like high temperatures and toxic solvents are used to modify inert materials, then modification is achieved, but the process becomes complex and environmentally harmful

Engineering Contradiction:
Improvematerial modification effectivenessVSAvoidtoxic solvents and high temperatures
Core Design Contradiction:
ReliabilityVSObject-affected harmful factors

Solution Approach 1:

The invention converts the inertness of the polyaramid material, which is normally a disadvantage preventing modification, into a benefit by using a basic pH buffer that does not require harsh conditions. The gentle basic environment allows the spider silk proteins to adhere to and modify the inert surface without requiring toxic solvents or high temperatures, thus converting the material's resistance into a platform for mild modification.

Inventive Principle:
Principle #22Blessing in disguise (Convert harm into benefit)

Solution Approach 2:

The invention uses a simple, inexpensive basic pH buffer solution (such as carbonate or phosphate buffer) as the coating medium, replacing complex and expensive harsh chemical systems. The buffer can be easily prepared and disposed of, eliminating the need for expensive specialized solvents and extreme condition equipment.

Inventive Principle:
Principle #27Cheap short-living objects (Disposable)

3Strength

If inert synthetic or inorganic materials are used, then chemical resistance and lightweight properties are achieved, but the materials are only slightly wettable and cannot be modified after polymerization under mild conditions

Engineering Contradiction:
Improvechemical resistance and lightweight propertiesVSAvoidpost-polymerization modification capability
Core Design Contradiction:
StrengthVSAdaptability or versatility

Solution Approach 1:

The invention applies the spider silk protein coating as a preliminary action on the inert polyaramid material before final application. This pre-coating step introduces functional amino acid residues that enable subsequent molecule attachment and modification under mild conditions, thus preparing the inert surface for future adaptability without compromising its inherent strength and chemical resistance.

Inventive Principle:
Principle #10Preliminary action

4Adaptability or versatility

If spider silk polypeptide coating is applied under mild conditions, then molecule attachment under non-destroying conditions is enabled, but the coating process requires specific pH buffer conditions

Engineering Contradiction:
Improvemolecule attachment capabilityVSAvoidpH buffer control requirements
Core Design Contradiction:
Adaptability or versatilityVSDevice complexity

Solution Approach 1:

The invention uses a basic pH buffer (pH 8-10) to dissolve spider silk proteins and create a coating solution that maintains protein solubility and reactivity. This specific pH parameter enables the amino acid residues to remain ionized and capable of forming chemical bonds with the polyaramid surface and with other molecules, thus facilitating versatile molecule attachment under mild, non-destroying conditions.

Inventive Principle:
Principle #35Parameter changes

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The spider silk-coated polyaramid materials exhibit enhanced surface feel, molecule attachment capabilities, and maintain the strength and elasticity of the underlying material while providing a smooth and appealing texture.

Implementation Method 1

applying the solution on a polyaramid material and thereby coating the polyaramid material with the spider silk polypeptide

Methodology Applied
Scientific EffectAdsorption: Adsorption

Data Source

PatentEP3495381B1Silk protein coatings
Publication Date: 2026.04.01 AMSILK
  • EP3495381B1 patent drawingFigure 1
  • EP3495381B1 patent drawingFigure 2
  • EP3495381B1 patent drawingFigure 3

AI summary

The present invention relates to a method for coating an inert or naturally occurring material with a silk polypeptide. It further relates to a coated inert or naturally occurring material obtainable by said method and to uses thereof. It also relates to products comprising said coated material.