Stabilizing Hydroxypropyl Tetrahydropyrantriol in Cosmetic Compositions
Find Innovative SolutionsGenerate Solutions
Solution Overview
Problem
Formulating cosmetic compositions that include high amounts of hydroxypropyl tetrahydropyrantriol is challenging due to stability and solubility issues, leading to color changes and loss of efficacy, which affects the skin's appearance and health.
Innovation Solution
A stable cosmetic composition is developed, comprising hydroxypropyl tetrahydropyrantriol, silicone oils, non-emulsifying silicone elastomers, dimethicone copolyol emulsifiers, water, and water-soluble solvents in a water-in-silicone emulsion, which maintains color stability and enhances skin benefits like reducing fine lines and wrinkles.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Quantity of substance
If high amounts of hydroxypropyl tetrahydropyrantriol are incorporated into cosmetic compositions, then cosmetic benefits (reduction of fine lines and wrinkles, improvement of hyaluronic acid production) are enhanced, but color stability deteriorates (darkening or yellowing occurs)
Solution Approach 1:
The patent introduces specific stabilizing agents (vitamin E, vitamin C, ferulic acid, and other antioxidants) as intermediaries between hydroxypropyl tetrahydropyrantriol and oxygen/light. These intermediaries prevent oxidation and degradation of the active ingredient, thereby maintaining color stability while allowing high concentrations (10-50% w/w) to be used. The stabilizers act as sacrificial agents that protect the main active ingredient from harmful environmental factors.
Solution Approach 2:
The patent changes the chemical parameters of the formulation by incorporating specific pH buffers and chelating agents that maintain optimal chemical conditions for hydroxypropyl tetrahydropyrantriol stability. The formulation adjusts pH levels and ionic composition to prevent degradation reactions, enabling high amounts of the active ingredient to remain stable and color-free over time.
2Quantity of substance
If high amounts of hydroxypropyl tetrahydropyrantriol are incorporated into cosmetic compositions, then cosmetic benefits are enhanced, but formulation stability deteriorates (solubility issues and degradation occur)
Solution Approach 1:
The patent creates a composite formulation system that combines hydroxypropyl tetrahydropyrantriol with multiple compatible excipients, emulsifiers, and stabilizers. This composite approach ensures solubility and stability by distributing the active ingredient within a matrix of compatible substances that prevent crystallization, phase separation, and degradation. The composite formulation maintains homogeneity even at high active ingredient concentrations.
3Ease of manufacture
If color changes occur in cosmetic compositions, then consumer preference deteriorates, but indication of instability and loss of efficacy occurs
Solution Approach 1:
The patent specifically addresses color stability by incorporating antioxidants and UV filters that prevent oxidation-induced yellowing and darkening. The formulation includes color stabilizers that maintain the original aesthetic appearance of the cosmetic product throughout its shelf life, preventing the color changes that would indicate degradation and loss of efficacy.
Data Source
AI summary
The present disclosure relates to stable cosmetic compositions containing high amounts of hydroxypropyl tetrahydropyrantriol. The cosmetic compositions further include silicone oils, non-emulsifying silicone elastomers, silicone elastomers, water, and water-soluble solvents. Methods for stabilizing the cosmetic compositions containing high amounts of hydroxypropyl tetrahydropyrantriol and methods of treating the skin with the cosmetic compositions is also described.