Stabilized Menthol Cannabinoid Gum via Undecylenic Acid

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Solution Overview

Problem

There is a need for effective delivery methods of cannabinoids and menthol that maintain their activity when incorporated into chewing gum or lozenges, addressing the inefficacy of current pain and inflammation treatments and the concern over opioid overuse.

Innovation Solution

A chewing gum or lozenge product containing cannabinoids and menthol, with a stabilized menthol composition using undecylenic acid methyl ester, undecylenic acid, or their salts, providing a unit dose formulation that includes full spectrum hemp oil and menthol, ensuring effective oral administration.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If therapeutic compounds such as cannabinoids and menthol are incorporated into chewing gum or lozenges, then effective delivery to the user is achieved, but maintaining their activity becomes difficult

Engineering Contradiction:
Improvetherapeutic activity maintenanceVSAvoidcompound stability in gum matrix
Core Design Contradiction:
ReliabilityVSStability of the object's composition

Solution Approach 1:

The patent employs encapsulation technologies and compatible carriers as intermediary substances to protect cannabinoids and menthol from degradation in the gum matrix. These intermediaries maintain the therapeutic compounds' activity while enabling their incorporation into the chewing gum or lozenge formulation.

Inventive Principle:
Principle #24Intermediary (Mediator)

Solution Approach 2:

The patent modifies physical and chemical parameters of the formulation, including pH control, oxidation prevention, and stability-enhancing additives, to maintain the therapeutic activity of cannabinoids and menthol throughout the product's shelf life and during use.

Inventive Principle:
Principle #35Parameter changes

2Reliability

If current pain and inflammation treatments are used, then pain relief is achieved, but unacceptable side effects occur

Engineering Contradiction:
Improvepain relief efficacyVSAvoidside effects
Core Design Contradiction:
ReliabilityVSObject-generated harmful factors

Solution Approach 1:

The patent utilizes cannabinoids and menthol, which provide pain relief and anti-inflammatory effects through different mechanisms than traditional opioids, thereby achieving therapeutic efficacy with a more favorable side effect profile. The specific dosing ranges and formulation parameters are optimized to maximize benefit while minimizing adverse effects.

Inventive Principle:
Principle #35Parameter changes

3Reliability

If opioids are used for pain treatment, then effective pain relief is achieved, but overuse concerns arise

Engineering Contradiction:
Improvepain relief efficacyVSAvoidopioid consumption volume
Core Design Contradiction:
ReliabilityVSQuantity of substance

Solution Approach 1:

The patent provides alternative pain management through cannabinoids and menthol formulations that can effectively treat pain without contributing to opioid overuse. The unit dose formulations enable precise control of therapeutic input, providing effective pain relief while avoiding the public health crisis associated with opioid dependency and overconsumption.

Inventive Principle:
Principle #35Parameter changes

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The product effectively delivers cannabinoids and menthol for pain relief and inflammation management, offering a novel treatment option with reduced side effects and avoiding opioid-related concerns.

Implementation Method 1

a stabilized menthol composition including menthol and at least one menthol stabilizer compound including undecylenic acid methyl ester, undecylenic acid or a salt of undecylenic acid

Methodology Applied
Scientific EffectStabilization:

Data Source

PatentUS11376227B2Cannabinoid and menthol gum and lozenge compositions and methods
Publication Date: 2022.07.05 GHALILI BABAK
  • US11376227B2 patent drawing
  • US11376227B2 patent drawing
  • US11376227B2 patent drawing

AI summary

The present disclosure relates to chewing gum or lozenge with cannabinoids and menthol including a liquid-filled chewing gum or lozenge with a chewing gum base shell or lozenge candy shell enclosing an internal void therein and a liquid filling in the void, the liquid-filled chewing gum or lozenge including cannabinoids and menthol. The menthol component can be a stabilized menthol composition comprising menthol and at least one menthol stabilizer compound including undecylenic acid methyl ester, undecylenic acid or a salt of undecylenic acid.