Stack Sensor Device for Compact Multi-Substrate Cell Culture Detection
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Solution Overview
Problem
Existing sensor devices require a larger apparatus configuration to detect changes in multiple substrates in a culture solution, as they need multiple sensor layers arranged horizontally, which complicates the setup.
Innovation Solution
A stack sensor configuration is used, where a second sensor layer is stacked on a first sensor layer, allowing for the detection of multiple substrates in a compact format, with the second sensor layer having higher transmittance than the first and potentially containing different optically active substances to react with various substrates, including oxygen and hydrogen ions.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Adaptability or versatility
If multiple sensor layers are arranged horizontally to detect changes in multiple substrates, then the detection capability for multiple substrates is improved, but the apparatus configuration becomes larger and more complex
Solution Approach 1:
The patent transitions from horizontal arrangement of sensor layers to a vertical stacked configuration. The first sensor layer detecting the first substrate and the second sensor layer detecting the second substrate are arranged in the vertical direction, with the second sensor layer positioned above the first sensor layer. This dimensional change from horizontal to vertical arrangement maintains the ability to detect multiple substrates while significantly reducing the lateral footprint and simplifying the overall apparatus configuration.
2Device complexity
If the second sensor layer is stacked on the first sensor layer to miniaturize the device, then the apparatus configuration becomes compact, but the transmittance of substrates may be affected
Solution Approach 1:
The patent applies local quality by giving different transmittance characteristics to different sensor layers based on their specific detection needs. The second sensor layer is designed with higher transmittance for the first substrate compared to the first sensor layer's transmittance for the second substrate. This localized optimization of transmittance properties ensures that each sensor layer can effectively detect its target substrate while maintaining the compact stacked structure.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
This configuration enables the detection of multiple substrates in a culture solution with improved spatial resolution and minimizes the risk of optically active substances leaking into the culture solution, thus protecting cells and simplifying the apparatus design.
Implementation Method 1
the first sensor layer may contain a first optically active substance that reacts with oxygen being the first substrate
Implementation Method 2
the second sensor layer may contain a second optically active substance that reacts with a hydrogen ion being the second substrate
Implementation Method 3
The second sensor layer may have a transmittance of the first substrate higher than that of the first sensor layer
Data Source
AI summary
A sensor device according to the present technology includes a stack sensor. The stack sensor includes a first sensor layer and a second sensor layer. The first sensor layer has, as a detection target, a first substrate in a culture solution, the first substrate being changed in accordance with a change in a state of a cell. The second sensor layer has, as a detection target, a second substrate in the culture solution and is provided on the first sensor layer, the second substrate being changed in accordance with the change in the state.