Stage-Specific Neurodevelopment Food Compositions for Infant Brain Growth

Resolve Bottlenecks,
Find Innovative Solutions
Generate Solutions

Solution Overview

Problem

Existing food compositions fail to provide essential nutrients during specific neurodevelopmental windows, leading to potential brain developmental issues and long-term neurological disorders.

Innovation Solution

Formulated food compositions containing specific nutrients tailored to support brain development during critical periods, including lutein, DHA, iron, zinc, copper, choline, vitamins, and minerals, administered at appropriate developmental stages to enhance neurodevelopment and prevent disorders.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If generic food compositions are provided to infants, then basic nutritional needs are met, but specific neurodevelopmental nutrient requirements during critical windows are not satisfied

Engineering Contradiction:
Improveneurodevelopmental supportVSAvoiddevelopmental stage specificity
Core Design Contradiction:
ReliabilityVSAdaptability or versatility

Solution Approach 1:

The patent divides infant nutrition into distinct developmental stages (0-6 months, 6-12 months, 12-24 months) with each stage having customized nutrient formulations. This segmentation allows each food composition to be optimized for specific neurodevelopmental windows, ensuring that critical nutrients are provided at the appropriate times when brain regions are most vulnerable and plastic.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The patent applies local quality by providing different nutrient compositions tailored to specific developmental stages and brain region requirements. Each age group receives a customized formulation with specific concentrations of DHA, ARA, iron, zinc, and other neurodevelopmental nutrients, rather than a uniform composition for all infants.

Inventive Principle:
Principle #3Local quality

2Reliability

If nutrient supplementation is delayed until after developmental windows close, then later nutritional needs may be addressed, but irreversible brain developmental dysfunction occurs

Engineering Contradiction:
Improvebrain development outcomeVSAvoiddevelopmental window opportunity
Core Design Contradiction:
ReliabilityVSLoss of time

Solution Approach 1:

The patent implements preliminary action by providing stage-specific nutrient formulations before critical developmental windows close. Each formulation is designed to be administered during the optimal time frame for supporting specific brain region development, ensuring that essential nutrients are present during the vulnerable periods when neural circuits are being established and cannot be easily modified later.

Inventive Principle:
Principle #10Preliminary action

Solution Approach 2:

The patent incorporates feedback mechanisms through developmental monitoring and age-appropriate formulation selection. The system tracks infant developmental stage and adjusts nutrient provision accordingly, ensuring that the right nutrients are provided at the right time based on the infant's current developmental needs and remaining sensitive periods.

Inventive Principle:
Principle #23Feedback

3Reliability

If comprehensive neurodevelopmental nutrients are provided at all stages, then brain development is supported, but nutrient overload or imbalances may occur during specific windows

Engineering Contradiction:
Improveneurodevelopmental supportVSAvoidnutrient dosage accuracy
Core Design Contradiction:
ReliabilityVSManufacturing precision

Solution Approach 1:

The patent applies dynamics by making nutrient compositions adjustable and stage-specific rather than static and universal. Each formulation dynamically adapts to the infant's developmental stage, with nutrient concentrations and types changing according to the specific requirements of each developmental window, preventing both deficiency and overload.

Inventive Principle:
Principle #15Dynamics

Solution Approach 2:

The patent implements parameter changes by modifying nutrient concentrations, ratios, and compositions based on developmental stage. Specific parameters such as DHA content, iron levels, and zinc concentrations are adjusted for each age group to match the precise nutritional requirements during different neurodevelopmental periods, ensuring optimal absorption and utilization without overload.

Inventive Principle:
Principle #35Parameter changes

Data Source

PatentUS12501923B2Neurodevelopment-promoting food compositions and kits, systems and methods related thereto
Publication Date: 2025.12.23 THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIV
  • US12501923B2 patent drawing
  • US12501923B2 patent drawing
  • US12501923B2 patent drawing

AI summary

Provided are food compositions configured to promote neurodevelopment in developing subjects. Food compositions of the present disclosure may make available to a subject those nutrients that are required by or otherwise positively influence developing brain regions, and the neurons thereof, during specific windows of neurodevelopment. Also provided are kits and systems that relate to the subject food compositions as well as methods, such as methods of formulating the described food compositions.