Stannous Oral Care Composition With Taurate for Stable Plaque Control

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Solution Overview

Problem

Existing dentifrice compositions face challenges with the unintended reactivity of anti-bacterial agents, such as zinc salts, leading to instability, unpleasant mouthfeel, and irritation, while formulations without sodium lauryl sulfate (SLS) are sought for improved oral health benefits without compromising gingival epithelium integrity.

Innovation Solution

An oral care composition comprising stannous ion source and taurate surfactant, free of zinc ions, enhances biofilm penetration and bacterial kill, providing improved stability, aesthetics, and reduced irritation.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If zinc salt is used as anti-bacterial agent, then plaque control is improved, but formulation stability deteriorates due to unintended reactivity with fluoride ions and anionic surfactants

Engineering Contradiction:

Improveplaque controlVSAvoidformulation stability

Core Design Contradiction:

ReliabilityVSStability of the object's composition

Solution Approach 1:

The invention removes zinc salt from the formulation entirely, replacing it with a stannous ion source. This extraction eliminates the harmful reactions between zinc ions and fluoride ions or anionic surfactants that cause formulation instability, while maintaining anti-plaque efficacy through stannous ions.

Inventive Principle:

Principle #2Taking out (Extraction)

Solution Approach 2:

The invention changes the type of metal ion parameter in the formulation from zinc ions to stannous ions. This parameter change resolves the reactivity issues with fluoride and surfactants while preserving the anti-bacterial and plaque control functions.

Inventive Principle:

Principle #35Parameter changes

2Productivity

If sodium lauryl sulfate is used as surfactant, then foaming and cleaning performance are improved, but gingival epithelium integrity deteriorates due to potential irritation

Engineering Contradiction:

Improvecleaning performanceVSAvoidgingival irritation

Core Design Contradiction:

ProductivityVSObject-affected harmful factors

Solution Approach 1:

The invention replaces sodium lauryl sulfate with a taurate surfactant, changing the surfactant type parameter. Taurate surfactants provide comparable foaming and cleaning performance but with reduced irritation to the gingival epithelium, thus resolving the contradiction between cleaning efficacy and tissue safety.

Inventive Principle:

Principle #35Parameter changes

3Reliability

If stannous fluoride is used for bactericidal effect, then plaque bacteria control is improved, but formulation stability deteriorates due to oxidative degradation

Engineering Contradiction:

Improvebactericidal effectVSAvoidformulation stability

Core Design Contradiction:

ReliabilityVSStability of the object's composition

Solution Approach 1:

The invention separates the stannous ion source from fluoride ions, eliminating the stannous fluoride compound that is prone to oxidative degradation. This extraction of the unstable compound maintains the bactericidal efficacy of stannous ions while removing the formulation stability issues associated with stannous fluoride.

Inventive Principle:

Principle #2Taking out (Extraction)

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The combination of stannous ions and taurate surfactant achieves deep biofilm penetration, effective bacterial kill, and toxin neutralization, while maintaining gingival health and stability across various conditions.

Implementation Method 1

the penetration depth and/or penetration rate of stannous ion/zinc ion into the biofilms may be increased

Methodology Applied

Scientific EffectBiofilm penetration: Permeation

Implementation Method 2

Stannous fluoride has both, bactericidal and bacteriostatic effect on plaque bacteria

Methodology Applied

Scientific EffectBactericidal effect:

Implementation Method 3

an aqueous oral care composition comprising stannous ion source and a taurate surfactant

Methodology Applied

Scientific EffectSurfactant action: Surfactant

Implementation Method 4

the synergistic combination of taurate and stannous ion source in the oral care composition may be such that an improvement in the Gum Health benefit is achieved

Methodology Applied

Scientific EffectSynergistic combination:

Implementation Method 5

It also has been shown to decrease biofilm virulence of the bacterial endotoxins like lipopolysaccharide (LPS) and lipoteicoic acid (LTA)

Methodology Applied

Scientific EffectToxin neutralization:

Implementation Method 6

Brushing with stannous fluoride toothpaste leads to reduction of gingivitis and as a result restoration of barrier function, what makes the gum tissue more resistance to bacteria attacks

Methodology Applied

Scientific EffectBarrier function restoration:

Data Source

PatentUS20260027028A1Oral care compositions for promoting gum health

Publication Date: 2026.01.29 PROCTER & GAMBLE CO

AI summary

Oral care compositions comprising a stannous ion source, a taurate surfactant and substantially free of a zinc ion source, which are effective in treating dental plaque biofilm and neutralizing bacterial toxins, while providing an improved sensorial experience.