Steerable Transcranial Stimulation Tag for Memory Consolidation

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Solution Overview

Problem

Existing transcranial stimulation systems for memory consolidation require a large number of electrodes, making them cumbersome and difficult to apply, especially for non-specialists, and necessitate precise electrode placement and electrical properties, limiting their use in everyday applications outside clinical settings.

Innovation Solution

A system using a minimum of four electrodes to generate a steerable, localized transcranial stimulation tag that can be applied during task acquisition and replayed during slow-wave sleep, allowing for a focal area of stimulation that can be moved and varied in intensity and size, reducing the number of electrodes needed and allowing for portable, easy application.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If a large number of electrodes (64-256) are used to create unique STAMP patterns for memory consolidation, then memory consolidation efficacy is improved, but device complexity and ease of operation deteriorate

Engineering Contradiction:
Improvememory consolidation efficacyVSAvoidnumber of electrodes
Core Design Contradiction:
ReliabilityVSDevice complexity

Solution Approach 1:

The patent segments the high-density electrode array into a smaller set of representative electrodes that can reproduce the essential STAMP pattern characteristics. By using only a subset of electrodes (e.g., 4-16 instead of 64-256), the system maintains the ability to create unique stimulation patterns while dramatically reducing complexity and ease of application.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The patent creates a simplified copy or representation of the full electrode array's functionality using fewer electrodes. The reduced electrode set is designed to replicate the spatial and temporal modulation capabilities of the full array, allowing the same memory consolidation effect to be achieved with much simpler hardware.

Inventive Principle:
Principle #26Copying

2Reliability

If many electrodes are applied to create and recreate STAMP patterns for memory consolidation, then memory consolidation efficacy is improved, but ease of operation and time required for application deteriorate

Engineering Contradiction:
Improvememory consolidation efficacyVSAvoidease of application
Core Design Contradiction:
ReliabilityVSEase of operation

Solution Approach 1:

The patent divides the complex task of applying and repositioning many electrodes into a simpler process using fewer electrodes. The reduced electrode count (4-16) can be applied and repositioned much more quickly and easily by non-specialists, while still achieving the necessary STAMP pattern modulation for memory consolidation.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The patent uses a partial set of electrodes that provides sufficient functionality for memory consolidation without requiring the full complement of 64-256 electrodes. This partial action approach achieves the necessary therapeutic effect with significantly reduced operational complexity.

Inventive Principle:
Principle #16Partial or excessive action

3Measurement precision

If high-density electrodes with gel are used for memory consolidation, then stimulation precision is improved, but ease of manufacture and portability deteriorate

Engineering Contradiction:
Improvestimulation precisionVSAvoidease of application
Core Design Contradiction:
Measurement precisionVSEase of manufacture

Solution Approach 1:

The patent extracts the essential stimulation functionality from the complex high-density electrode system. By removing the majority of electrodes and their associated gel application requirements, the system maintains stimulation precision for memory consolidation while eliminating the messy and time-consuming application process.

Inventive Principle:
Principle #2Taking out (Extraction)

Solution Approach 2:

The patent employs simpler, more portable electrode designs that can be easily applied and removed without the complex setup required for high-density arrays. These simplified electrodes can be used by non-specialists in everyday settings, improving ease of manufacture and portability while maintaining therapeutic efficacy.

Inventive Principle:
Principle #27Cheap short-living objects (Disposable)

4Reliability

If electrodes must be applied with gel and replaced regularly, then stimulation reliability is improved, but loss of time and ease of operation increase

Engineering Contradiction:
Improvestimulation reliabilityVSAvoidtime for electrode application and replacement
Core Design Contradiction:
ReliabilityVSLoss of time

Solution Approach 1:

The patent removes the gel application step from the electrode setup process, significantly reducing the time required for both initial application and daily repositioning. The simplified electrode design maintains sufficient contact with the scalp to deliver reliable stimulation without requiring the time-consuming gel application process.

Inventive Principle:
Principle #2Taking out (Extraction)

Solution Approach 2:

The patent uses a partial electrode set that requires much less time for application and replacement compared to full-density arrays. The reduced number of electrodes (4-16) can be quickly positioned and repositioned daily without the extensive time investment required for managing 64-256 electrodes with gel.

Inventive Principle:
Principle #16Partial or excessive action

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

This approach simplifies the application of memory consolidation technology, making it more accessible for everyday use by reducing the number of electrodes required, allowing for steerable and targeted stimulation, and increasing the efficacy of memory reactivation during sleep, thus facilitating quicker integration and recall of information.

Implementation Method 1

A system using a minimum of four electrodes to generate a steerable, localized transcranial stimulation tag that can be applied during task acquisition and replayed during slow-wave sleep, allowing for a focal area of stimulation that can be moved and varied in intensity and size

Methodology Applied
Scientific EffectTranscranial electrical stimulation: Electric Field

Data Source

PatentUS10596372B2Targeted steerable transcranial intervention to accelerate memory consolidation
Publication Date: 2020.03.24 HRL LAB
  • US10596372B2 patent drawing
  • US10596372B2 patent drawing
  • US10596372B2 patent drawing

AI summary

Described is a system to accelerate memory consolidation using a steerable transcranial intervention. During operation, the system generates a unique transcranial and steerable stimulation tag to associate with memory of a task or event. Once the tag is generated, the system activates a plurality of electrodes (e.g., as few as four) to apply the unique transcranial stimulation tag during the occurrence of the event or task to be consolidated.