Stem Cell Delivery Device for Spinal Cord Injury Repair
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Solution Overview
Problem
Current treatments for spinal cord injuries, involving intravenous or subarachnoid infusion of stem cells, are ineffective due to insufficient stem cell delivery to the injury site, hindering meaningful recovery.
Innovation Solution
A method and device combination that allows direct delivery of stem cells and adipose tissue to the spinal injury site by inserting a Dacron Catheter into the epidural space, using a Pressure Metered Syringe Injector to inject stem cells mixed with PRP into the subarachnoid space, facilitating the growth of new spinal tracts to reconnect damaged areas.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Quantity of substance
If stem cells are infused intravenously or injected into the subarachnoid space, then the treatment can be administered, but too few stem cells reach the injured spinal site to restore meaningful function
Solution Approach 1:
The patent uses adipose tissue as an intermediary vehicle to transport stem cells directly to the injured spinal site. The adipose tissue is injected into the epidural space and acts as a carrier that releases stem cells at the target location, ensuring sufficient quantity reaches the injury site while maintaining treatment reliability
Solution Approach 2:
The patent performs preliminary injection of adipose tissue into the epidural space before injecting the stem cells into the subarachnoid space. This preliminary action creates a pathway and ensures that the stem cells will be retained and delivered to the injury site, preventing loss and ensuring adequate delivery quantity
Data Source
AI summary
The Stem Cell Delivery Device comprises an Introducer, a Catheter, and Pressure Metered Injector Syringe. The device and method aim to deliver stem cells abundantly enough at the damaged site to allow recovery and restore function. The Method uses activated Stem Cells. It entails injecting via the Syringe Injector the epidural space with raw adipose tissue extract to circle the spinal cord about a level above and below the injured cord site till blockade of the subarachnoid space of the injured spinal cord site is achieved and radiographically verified. Then washed activated stem cells are injected via the Syringe into the blocked subarachnoid space to bridge between the upper and lower normal spinal tract, allowing the stem cells to grow new spinal tracts to connect and bridge over the damaged site. IV infusion of bone marrow stem cells is added to maximize the chance of recovery.