Hierarchical Stem Cell Density Calculation Using Multi-Ratio Image Reduction

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Solution Overview

Problem

Existing methods for calculating the density of stem cells in images are inefficient, requiring significant processing and difficulty in detecting both high and low-density stem cells.

Innovation Solution

A method using electronic devices with pre-trained density calculation models and hierarchical image reduction techniques, where images are resized based on preset ratios to apply corresponding models for efficient density estimation, allowing for quick detection of stem cell densities across various ranges.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Productivity

If known methods are used to calculate the number and volume of stem cells in an image, then the density can be calculated, but the processing efficiency is low

Engineering Contradiction:
Improvecalculation efficiencyVSAvoidprocessing time
Core Design Contradiction:
ProductivityVSLoss of time

Solution Approach 1:

The patent segments the image processing task into multiple density ranges, creating different processing models for high-density and low-density stem cell images. This segmentation allows each model to be optimized for its specific range, improving overall processing efficiency while maintaining accuracy for different cell densities

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The patent changes the processing parameters (image resolution, processing intensity) based on the density range of stem cells. For high-density images, one set of parameters is used, while for low-density images, different parameters are applied. This dynamic parameter adjustment significantly improves calculation efficiency without sacrificing measurement precision

Inventive Principle:
Principle #35Parameter changes

2Productivity

If standard processing methods are applied to all images, then consistency is maintained, but efficiency decreases due to unnecessary processing of high-density images

Engineering Contradiction:
Improveprocessing speedVSAvoiddensity calculation accuracy
Core Design Contradiction:
ProductivityVSMeasurement precision

Solution Approach 1:

The patent applies local quality by using different processing strategies for different regions of the density space. High-density images receive one type of processing optimization, while low-density images receive another type. This ensures that each image is processed with the most appropriate method for its characteristics, maintaining precision while improving speed

Inventive Principle:
Principle #3Local quality

Data Source

PatentUS12111244B2Method for calculating a density of stem cells in a cell image, electronic device, and storage medium
Publication Date: 2024.10.08 HON HAI PRECISION INDUSTRY CO LTD
  • US12111244B2 patent drawing
  • US12111244B2 patent drawing

AI summary

A method for calculating a density of stem cells in a cell image and an electronic device are provided. A plurality of preset ratios and a plurality of density calculation models can be used to perform hierarchical density calculations on the cell image. Starting from the largest preset ratio (the first preset ratio) reduction of the cell image to no reduction, the density calculation is performed on the cell image using a model starting with a highest density calculation (the first density calculation model) to a model with the smallest density calculation (the third density calculation model), which can quickly detect densities of various stem cells. Using different preset ratios and corresponding density calculation models for calculation, it is not necessary to calculate the number of stem cells to obtain the density of stem cells, which improves a calculation efficiency of the density of stem cells.