Stereoscopic 3D DBT Volume for Microcalcification Analysis

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Solution Overview

Problem

Current 3D mammography techniques, such as digital breast tomosynthesis (DBT), face challenges in reliably discerning the 3D distribution of microcalcifications, which are indicative of ductal carcinoma in situ (DCIS) or benign, due to their appearance as clusters in two-dimensional arrays, making it difficult for radiologists to identify suspicious branching structures.

Innovation Solution

The implementation of a geo-registered 3D DBT volume viewed through true stereoscopic imaging and augmented/virtual reality, allowing rotation, zooming, and interaction with the data, combined with varying breast compression levels to analyze morphologic changes, enables a comprehensive understanding of microcalcifications and tumorous tissue distribution.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Measurement precision

If microcalcifications are viewed in 2D arrays on mammograms or DBT images, then the imaging process remains simple and quick, but the ability to discern the 3D distribution and branching structures of microcalcifications is severely limited

Engineering Contradiction:
Improveability to discern 3D distribution of microcalcificationsVSAvoidcomplexity of 3D visualization system
Core Design Contradiction:
Measurement precisionVSDevice complexity

Solution Approach 1:

The patent transforms 2D mammogram and DBT images into a 3D virtual model that radiologists can navigate and examine from multiple angles. This dimensional transformation allows microcalcifications to be visualized in their true 3D spatial distribution, revealing branching structures and patterns that are invisible in 2D projections. The system creates a volumetric representation where radiologists can rotate, zoom, and fly through the breast tissue model to examine microcalcification clusters from any perspective.

Inventive Principle:
Principle #17Another dimension (Dimensionality change)

2Reliability

If multiple compression levels are applied to analyze morphologic changes, then diagnostic accuracy improves, but the examination time and procedural complexity increase

Engineering Contradiction:
Improvediagnostic accuracyVSAvoidexamination time
Core Design Contradiction:
ReliabilityVSLoss of time

Solution Approach 1:

The system performs preliminary 3D virtual modeling and microcalcification detection during the initial imaging process. By pre-processing the images to create an accurate 3D virtual model with identified microcalcifications, the system enables rapid diagnostic evaluation without requiring multiple sequential examinations. Radiologists can immediately interact with the pre-generated 3D model to analyze morphologic changes across different compression levels, reducing the need for repeated imaging procedures.

Inventive Principle:
Principle #10Preliminary action

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

This approach enhances radiologists' ability to accurately differentiate between benign and malignant microcalcifications by providing a thorough 3D visualization and analysis of breast tissue structures, reducing false positives and improving diagnostic accuracy.

Implementation Method 1

the X-ray machine sweeps out an arc taking multiple X-rays while the breast is compressed by a paddle against the X-ray detector plate

Methodology Applied
Scientific EffectX-ray: X-Ray

Implementation Method 2

digital breast tomosynthesis (DBT). DBT differs from a common mammogram in that with DBT, the X-ray machine sweeps out an arc taking multiple X-rays

Methodology Applied
Scientific EffectTomography: Tomography

Data Source

PatentUS10973485B1Enhanced volume viewing
Publication Date: 2021.04.13 TIPPING POINT MEDICAL IMAGES LLC
  • US10973485B1 patent drawing
  • US10973485B1 patent drawing
  • US10973485B1 patent drawing

AI summary

A method for improved 3D imaging of a volume is disclosed. The application discussed is improved assessment of complex 3D structures including breast microcalcifications and incorporation of geo-registered tools. The 3D imaging is displayed on a geo-registered head display unit.