Sterile Cassette Loading for Solid Dose Injection Devices

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Solution Overview

Problem

Existing injection devices for solid dose formulations require manual handling of cassettes, compromising sterility and leading to user errors, and disposal of medical tools is costly and environmentally undesirable.

Innovation Solution

An injection device with a cassette holder and actuator design that allows for sterile handling by preventing direct contact with the cassette, featuring a bayonet fitting and locking mechanism to maintain sterility and reduce user errors, with the cassette and holder components being separable for safe disposal.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Ease of operation

If users manually handle the cassette to load it into the actuator, then the user can control the loading process, but the sterility of the cassette is compromised and user errors increase

Engineering Contradiction:
ImproveUser control over loading processVSAvoidSterility maintenance and error reduction
Core Design Contradiction:
Ease of operationVSReliability

Solution Approach 1:

A robotic arm serves as an intermediary between the cassette storage and the actuator, automatically transferring the cassette without human handling. This mediator performs the loading operation precisely and sterilely, eliminating user errors while maintaining sterility throughout the process

Inventive Principle:
Principle #24Intermediary (Mediator)

Solution Approach 2:

The system performs self-service through automated operations where the robotic arm independently retrieves cassettes from storage and loads them into the actuator without requiring user intervention. The system serves itself by automating the entire loading process, ensuring both sterility and error-free operation

Inventive Principle:
Principle #25Self-service

2Ease of manufacture

If the cassette and actuator are disposed of together after use, then disposal is simplified, but the expensive actuator is wasted along with the single-use cassette

Engineering Contradiction:
ImproveDisposal simplicityVSAvoidWaste of expensive actuator material
Core Design Contradiction:
Ease of manufactureVSLoss of substance

Solution Approach 1:

The system segments the disposal process by separating the cassette from the actuator. The cassette is designed as a disposable component that can be independently removed and discarded, while the expensive actuator remains intact for reuse. This segmentation allows differential disposal strategies based on component value and usage lifecycle

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The system implements discarding and recovering by deliberately discarding only the low-value cassette after single use, while recovering and retaining the high-value actuator for subsequent reuse. This selective discarding strategy optimizes resource utilization by wasting only what is necessary

Inventive Principle:
Principle #34Discarding and recovering

3Reliability

If demonstration training is provided to users, then user errors are reduced, but the time and resources required for training increase

Engineering Contradiction:
ImproveReduction of user errorsVSAvoidTime required for demonstration and training
Core Design Contradiction:
ReliabilityVSLoss of time

Solution Approach 1:

The robotic arm enables the system to perform cassette loading automatically without requiring user training or demonstration. The automation serves the function of cassette management itself, eliminating the need for human learning curves or training programs while maintaining high reliability

Inventive Principle:
Principle #25Self-service

Data Source

PatentEP3253439B1Injection device
Publication Date: 2026.04.29 AVAXZIPEN LTD
  • EP3253439B1 patent drawingFigure 1
  • EP3253439B1 patent drawingFigure 2~3
  • EP3253439B1 patent drawingFigure 4

AI summary

An injection device for injecting a solid dose formulation into a human or animal body, the injection device comprising an actuator (10) having a cassette mounting portion (14); a cassette holder (20) having a cassette storage portion; and a cassette selectively movable between the cassette storage portion and the cassette mounting portion, wherein, the cassette (34) comprises a solid dose formulation and the actuator is receivable in the cassette holder to selectively move the cassette between the cassette storage portion and the cassette mounting portion.