Integrated Skin Sterilization Patch for Large Volume Medicament Delivery

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Solution Overview

Problem

Current large volume medicament injection devices are cumbersome and risk incorrect use due to complex multi-step processes, including sterilization, and may cause patient discomfort or pharmacokinetic issues when administering high viscosity biological medicaments.

Innovation Solution

A medicament delivery device with a moveable sterilizing pad that sweeps across the skin, integrated into the device for efficient sterilization, and safety features to prevent needle injection before sterilization, allowing for simpler and safer administration of large volumes of medicament.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If a multi-step sterilization process is used before injection, then sterilization effectiveness is improved, but device complexity and ease of operation deteriorate

Engineering Contradiction:
Improvesterilization effectivenessVSAvoidprocess complexity
Core Design Contradiction:
ReliabilityVSDevice complexity

Solution Approach 1:

The patent combines the sterilization function and injection function into a single integrated device. The housing contains both the sterilizing mechanism (with sterilizing liquid reservoir and applicator) and the injection mechanism (with needle and medicament reservoir), allowing both functions to be performed using one device rather than requiring separate sterilization materials and injection device

Inventive Principle:
Principle #5Merging (Combining)

Solution Approach 2:

The sterilization step is built into the device workflow before injection. The device is designed to perform sterilization of the injection site as a preliminary action before the injection can proceed, ensuring proper sterilization is completed as part of the overall process rather than as a separate preparatory step

Inventive Principle:
Principle #10Preliminary action

2Adaptability or versatility

If a multi-step assembly process is required, then device functionality is improved, but ease of operation and time consumption worsen

Engineering Contradiction:
Improvedevice functionalityVSAvoiduser simplicity
Core Design Contradiction:
Adaptability or versatilityVSEase of operation

Solution Approach 1:

The patent integrates multiple functions (sterilization, injection, medicament delivery) into a single unified device structure. The housing contains all necessary components including the sterilizing liquid reservoir, sterilizing applicator, needle, and medicament reservoir, eliminating the need for users to assemble multiple separate components

Inventive Principle:
Principle #5Merging (Combining)

Solution Approach 2:

The device is designed as a multi-functional unit that can perform sterilization, injection, and medicament delivery all in one device. This universal design allows a single device to replace multiple separate tools and materials that would otherwise be needed

Inventive Principle:
Principle #6Universality (Multi-functionality)

3Quantity of substance

If large volumes of medicament are injected, then treatment capacity is improved, but patient discomfort and injection time worsen

Engineering Contradiction:
Improvemedicament volumeVSAvoidpatient discomfort
Core Design Contradiction:
Quantity of substanceVSObject-affected harmful factors

Solution Approach 1:

The device is designed to deliver large volumes of medicament through a continuous injection process. The integrated design allows for sustained delivery of medicament over time, accommodating large volumes without requiring multiple separate injection events that would increase patient discomfort

Inventive Principle:
Principle #20Continuity of useful action

Data Source

PatentEP3193981B1Large volume skin patch medicament delivery device with integrated skin sterilization mechanism for the injection site
Publication Date: 2020.11.04 SANOFI SA(FR)
  • EP3193981B1 patent drawingFigure 1
  • EP3193981B1 patent drawingFigure 2~3
  • EP3193981B1 patent drawingFigure 4~5

AI summary

A skin-patch type medicament delivery device (10, 30, 50) comprises a housing (11) containing a medicament delivery mechanism (12) including an injection needle (13). An adhesive surface (19) is provided for securing the housing (11) to a patient's skin during a medicament delivery process. A sterilizing mechanism is connected to the housing (11) and thus integrated into the device, and comprises a pad (18) impregnated with sterilizing agent which contacts the skin once the housing (11) is secured to a patient, and which can, respectively has to be moved in a swiping action across the injection site to sterilize the latter before the needle insertion and drug administration can be performed.