Stevia Glycoside Solubility via Cyclodextrin Inclusion Complexes
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Solution Overview
Problem
Stevia glycosides have low aqueous solubility and tend to precipitate, leading to stability issues in solutions, which affects the potency and perception of sweetener formulations.
Innovation Solution
A sweetener composition comprising stevia glycosides and a natural emulsifier, such as Quillaja tree extract, enhances solubility and stability in aqueous solutions, preventing precipitation and maintaining clarity.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Loss of energy
If stevia glycosides are used as a sugar substitute, then caloric intake is reduced, but aqueous solubility and stability deteriorate
Solution Approach 1:
The patent uses cyclodextrins as intermediary molecules that form inclusion complexes with stevia glycosides. The cyclodextrin's hydrophilic exterior and hydrophobic interior create a stable complex that enhances aqueous solubility while maintaining the sweetening properties of stevia glycosides, thus resolving the contradiction between caloric reduction and solubility stability.
Solution Approach 2:
The invention creates a composite system combining stevia glycosides with cyclodextrins. This composite material leverages the low-caloric property of stevia while utilizing cyclodextrin's solubilizing capability to overcome the poor aqueous solubility and stability issues of pure stevia glycoside solutions.
2Loss of energy
If stevia glycosides are used as a sugar substitute, then caloric intake is reduced, but precipitation and co-precipitation worsen
Solution Approach 1:
Cyclodextrins act as mediators that prevent precipitation by forming stable soluble complexes with stevia glycosides. The cyclodextrin molecules surround the stevia glycoside molecules, preventing their aggregation and co-precipitation with other formulation components, thus eliminating the harmful precipitation effect while maintaining the low-caloric benefit.
Solution Approach 2:
The invention changes the physical-chemical parameters of the stevia glycoside system by introducing cyclodextrins, which alter the solubility product and prevent supersaturation-induced precipitation. This parameter change maintains the low-caloric advantage while eliminating precipitation issues.
3Quantity of substance
If higher concentrations of stevia glycosides are used to maintain potency, then sweetness intensity is improved, but solubility and stability worsen
Solution Approach 1:
Cyclodextrins serve as intermediaries that enable higher concentrations of stevia glycosides to remain in solution. By forming 1:1 inclusion complexes, cyclodextrins increase the effective solubility limit, allowing formulation of higher potency sweetener solutions without precipitation or stability degradation.
Solution Approach 2:
The introduction of cyclodextrins changes the concentration parameter at which precipitation occurs. The complex formation shifts the solubility equilibrium, enabling much higher stevia glycoside concentrations to be maintained in stable solution, thus achieving both high potency and stability.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
The solution allows for higher concentrations of stevia glycosides to remain dissolved, maintaining the sweetener's potency and clarity for extended periods, improving the stability and quality of sweetener formulations.
Implementation Method 1
The natural emulsifier of the sweetener composition may enhance the aqueous solubility of the stevia glycoside to increase the concentration of dissolved stevia glycoside relative to its inherent aqueous solubility
Data Source
AI summary
Various embodiments of the present technology provide a sweetener composition comprising stevia glycosides that may be stably soluble in an aqueous solution, and methods for their manufacture. In various embodiments, the sweetener composition may comprise at least one stevia glycoside and a natural emulsifier. The natural emulsifier of the sweetener composition may enhance the aqueous solubility of the stevia glycoside to increase the concentration of dissolved stevia glycoside relative to its inherent aqueous solubility. The sweetener composition may be stably soluble upon formulation into any edible sweetened substances.