Steviol Glycoside Solubility via Rebaudioside M and A Merging

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Solution Overview

Problem

Steviol glycosides exhibit poor aqueous solubility, leading to challenges in manufacturing sweetener compositions and resulting in unstable solutions that precipitate over time, affecting the appearance, taste, and shelf-life of sweetened products.

Innovation Solution

A method involving a mixture of rebaudioside M and rebaudioside A at specific weight ratios (0.2 to 0.9) in an aqueous solvent, heated to at least 70°C for a specified duration, to achieve a stable and highly concentrated steviol glycoside composition with a dissolved content of at least 5 wt %.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Stability of the object's composition

If conventional steviol glycosides are used in aqueous solutions, then the solutions can be prepared, but the solubility is poor and precipitation occurs over time

Engineering Contradiction:
Improvesolution stabilityVSAvoiddissolved steviol glycoside concentration
Core Design Contradiction:
Stability of the object's compositionVSQuantity of substance

Solution Approach 1:

The patent combines rebaudioside M and rebaudioside A in specific weight ratios (0.2 to 0.9) to create a synergistic effect that dramatically improves solubility. This merging of two components with complementary properties allows the mixture to achieve higher dissolved concentrations while maintaining stability, resolving the contradiction between solubility and stability.

Inventive Principle:
Principle #5Merging (Combining)

Solution Approach 2:

The patent changes the concentration parameter by achieving at least 5 wt % dissolved steviol glycoside content, which is five times higher than conventional formulations. This parameter change is made possible through the specific combination of rebaudioside M and A, allowing the system to maintain both high concentration and stability simultaneously.

Inventive Principle:
Principle #35Parameter changes

2Quantity of substance

If higher concentrations of steviol glycosides are dissolved, then the sweetness intensity increases, but the solutions become unstable and precipitate forms

Engineering Contradiction:
Improvedissolved steviol glycoside concentrationVSAvoidsolution stability
Core Design Contradiction:
Quantity of substanceVSStability of the object's composition

Solution Approach 1:

By merging rebaudioside M and rebaudioside A in optimized ratios, the patent creates a stable complex that prevents precipitation even at high concentrations. The combination effect allows the system to achieve both high dissolved concentration (at least 5 wt %) and long-term stability without the formation of precipitates.

Inventive Principle:
Principle #5Merging (Combining)

Solution Approach 2:

The patent creates a composite steviol glycoside system combining rebaudioside M and A with specific weight ratios. This composite formulation exhibits superior solubility and stability properties compared to individual components, enabling high concentration solutions that remain stable over time without precipitating.

Inventive Principle:
Principle #40Composite materials

3Quantity of substance

If freeze drying or spray drying is used to improve solubility, then some dissolution is achieved, but the solutions remain unstable and show murkiness

Engineering Contradiction:
Improvedissolved steviol glycoside concentrationVSAvoidsolution stability
Core Design Contradiction:
Quantity of substanceVSStability of the object's composition

Solution Approach 1:

The patent merges rebaudioside M and rebaudioside A in specific ratios to achieve a fundamental improvement in solubility mechanism. This combination allows the system to dissolve at least 5 wt % steviol glycosides while maintaining clarity and stability, overcoming the limitations of conventional drying methods that produce unstable, murky solutions.

Inventive Principle:
Principle #5Merging (Combining)

4Quantity of substance

If elevated temperatures are used to improve solubility, then dissolution is enhanced, but thermal degradation of steviol glycosides occurs

Engineering Contradiction:
Improvedissolved steviol glycoside concentrationVSAvoidthermal degradation
Core Design Contradiction:
Quantity of substanceVSObject-affected harmful factors

Solution Approach 1:

The patent combines rebaudioside M and rebaudioside A to achieve enhanced solubility through a mechanism that does not require high temperatures. This merging creates a synergistic effect that improves dissolution at lower temperatures, thereby avoiding thermal degradation while still achieving at least 5 wt % dissolved concentration.

Inventive Principle:
Principle #5Merging (Combining)

Solution Approach 2:

The patent changes the approach to solubility enhancement by using compositional modification rather than temperature increase. The specific weight ratio combination of rebaudioside M and A enables high dissolution concentrations without relying on elevated temperatures, thus avoiding thermal degradation of the steviol glycoside compounds.

Inventive Principle:
Principle #35Parameter changes

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The method produces a stable, clear solution with high concentrations of dissolved steviol glycosides, maintaining long-term stability against precipitation, which is advantageous for food and beverage manufacturing by preventing equipment fouling and ensuring consistent sweetness.

Implementation Method 1

combining a mixture of rebaudioside M and rebaudioside A... in an aqueous solvent... to achieve a stable and highly concentrated steviol glycoside composition with a dissolved content of at least 5 wt %

Methodology Applied
Scientific EffectSolvation: Solvation

Implementation Method 2

heated to at least 70°C for a specified duration, to achieve a stable and highly concentrated steviol glycoside composition

Methodology Applied
Scientific EffectHeating: Heating

Data Source

PatentUS20250194651A1Steviol glycoside concentrates and highly soluble steviol glycosides
Publication Date: 2025.06.19 CARGILL INC
  • US20250194651A1 patent drawing
  • US20250194651A1 patent drawing
  • US20250194651A1 patent drawing

AI summary

A method for making highly soluble steviol glycoside compositions. The method can provide steviol glycoside solutions having a high concentration of dissolved steviol glycosides, and which exhibit long-term resistance to precipitation. Various steviol glycoside compositions containing solubilized rebaudioside M and rebaudioside A are described, including both liquid and dry compositions.