Stimulus Trigger Adapter for EEG Latency Reduction

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Solution Overview

Problem

Existing methods for triggering stimuli in evoked brain response analysis, such as EEG and MEG, face significant latency issues due to hardware and operating system delays, which affect the accuracy of stimulus onset timing and subsequent data analysis.

Innovation Solution

An input/output adapter is developed to synchronize stimulus and trigger signals by encoding audio files with separate channels for trigger and stimulus data, allowing for precise timing and simultaneous delivery of these signals to EEG data loggers and audio playback devices, thereby minimizing latency.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Measurement precision

If audio playback is triggered by monitoring byte receipt at the sound card, then stimulus onset time can be estimated, but latency between audio file receipt and audio signal delivery to audio jack occurs (10-30 ms)

Engineering Contradiction:
Improvestimulus onset timing accuracyVSAvoidlatency between audio file receipt and audio signal delivery
Core Design Contradiction:
Measurement precisionVSLoss of time

Solution Approach 1:

The audio file is segmented into two separate channels: a first channel carrying trigger data and a second channel carrying stimulus data. This segmentation allows the trigger signal to be extracted independently from the stimulus signal, enabling precise timing without being affected by audio playback latency. The trigger channel can be processed separately to generate an accurate trigger event timestamp.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

A separate trigger signal generation mechanism is introduced as an intermediary between the audio playback system and the EEG recording system. The trigger signal is derived from the first channel of the encoded audio file and is delivered to the EEG data logger independently of the audio playback timing, serving as an accurate intermediary marker for stimulus onset without being affected by audio latency.

Inventive Principle:
Principle #24Intermediary (Mediator)

2Measurement precision

If trigger signal is delivered to EEG data logger simultaneously with audio signal, then timing accuracy is improved, but hardware complexity increases due to separate trigger generation circuitry

Engineering Contradiction:
Improvestimulus timing synchronizationVSAvoidadapter circuitry for separate trigger and stimulus signal generation
Core Design Contradiction:
Measurement precisionVSDevice complexity

Solution Approach 1:

The adapter is designed as a multi-functional device that simultaneously performs audio file decoding, trigger signal extraction, and stimulus signal generation. By integrating these multiple functions into a single adapter unit, the system achieves precise timing synchronization without requiring separate independent trigger generation hardware for each component, thus managing complexity while maintaining functionality.

Inventive Principle:
Principle #6Universality (Multi-functionality)

Data Source

PatentUS20220110578A1Methods and apparatus for triggering a stimulus for evoked brain response analysis
Publication Date: 2022.04.14 HEALTHTECH CONNEX INC
  • US20220110578A1 patent drawing
  • US20220110578A1 patent drawing
  • US20220110578A1 patent drawing

AI summary

Methods and apparatus are described for synchronizing a stimulus with EEG data for research and clinical and consumer applications using EEG and ECG devices. An input/output adapter for stimulus timing includes an adapter input port for receiving an encoded audio file played from an audio output device. The audio file has a first channel carrying trigger data and a second channel carrying stimulus data. The adapter is configured to separate the encoded audio file into its first and second channels; read the trigger data in the first channel and generate a trigger signal for delivery to an EEG data logger; and read the stimulus data in the second channel and generate an auditory signal for delivery to an audio playback device. Timing errors in regard to stimulus onsets are addressed by the synchronized transmission of the trigger signal and auditory signal.