Stomach Invagination via Adhesive Matrix and Suction
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Solution Overview
Problem
Current methods for addressing obesity, including gastric bypasses and implanted devices, have limitations in effectively reducing stomach volume and malabsorption, and biosurgical adhesives have not been utilized in a way that creates invaginated portions of the stomach to achieve these goals.
Innovation Solution
An invagination system comprising a suction device and an endoscopic adhesive applier is used to create invaginated portions of the stomach by applying an adhesive matrix to the outer stomach wall, which reduces stomach volume and can be maintained with sutures, allowing the invaginated portions to eventually separate and pass through the gastrointestinal tract, preventing reformation of openings.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Volume of stationary object
If gastric bypass or implanted devices are used to address obesity, then stomach volume is reduced, but the complexity of the procedure and device increases
Solution Approach 1:
The stomach is divided into multiple invaginated portions through the application of adhesive at specific locations, creating segmented compartments that reduce overall stomach volume. This segmentation approach avoids the complexity of gastric bypass surgery while achieving volume reduction through localized adhesive application and tissue invagination.
2Volume of stationary object
If gastric bypass is performed to reduce stomach volume, then malabsorption occurs, but the procedure complexity and risks increase
Solution Approach 1:
A biosurgical adhesive is used as an intermediary substance to create invaginated portions of the stomach wall. The adhesive is applied to the outer stomach wall, causing the tissue to fold inward and create volume-reducing compartments without requiring complex surgical bypass procedures, thereby simplifying the overall treatment approach.
3Volume of stationary object
If adhesives are applied to the outer stomach wall to create invaginated portions, then stomach volume is reduced, but the structural integrity of the stomach must be maintained
Solution Approach 1:
The adhesive is applied to the outer stomach wall before the invagination process is completed. This preliminary application allows the adhesive to bond the tissue layers together as they are pulled inward, maintaining structural integrity throughout the invagination process and ensuring the created portions remain stable without compromising the overall stomach structure.
4Area of stationary object
If invaginated portions are created to reduce acid-producing surface area, then malabsorbative effect is achieved, but the complexity of adhesive application increases
Solution Approach 1:
The adhesive is applied locally to specific regions of the outer stomach wall where invaginated portions are desired, rather than uniformly across the entire stomach surface. This localized application approach reduces the acid-producing surface area in targeted regions while keeping the adhesive application process simple and controlled.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
The system effectively reduces stomach volume and acid-producing surface area, providing a malabsorbative effect that complements the reduction in stomach volume, offering a treatment for obesity by maintaining the structural integrity of the stomach.
Implementation Method 1
an invagination system comprising a suction device and an endoscopic adhesive applier is used to create invaginated portions of the stomach
Data Source
AI summary
A system for creating an invaginated portion in a stomach comprises a suction device and a securing member. The suction device comprises a suction head operable to provide suction, a shaft connected to the suction head, and a vacuum lumen in fluid communication with the suction head. The suction head and vacuum lumen are operable to induce a vacuum adjacent to tissue. The suction device is further operable to create an invaginated portion with the tissue. The securing member is operable to substantially maintain the configuration of the invaginated portion of tissue. The suction device may comprise gripping jaw members having teeth. The securing member may comprise an adhesive and/or sutures and the like. The system may be used to create invaginated portions within a stomach. Such invaginated portions may reduce stomach volume to address obesity or other conditions.