Stomatological Composition Stabilizing Antibodies
Find Innovative SolutionsGenerate Solutions
Solution Overview
Problem
Existing stomatological compositions fail to stably contain antibodies from hen egg yolks and enzymes, making it difficult to effectively prevent or improve odontonecrosis and periodontal diseases.
Innovation Solution
A composition including lipase, protease, antibodies from hen egg yolks, citric acid, and metal salts of citric acid, with specific ratios and additional components like collagen and surfactants, to stabilize these components and enhance their functionality.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Reliability
If an antibody from hen egg yolk and an enzyme are contained in a stomatological composition, then the prevention or improvement of odontonecrosis and periodontal disease is enhanced, but the composition cannot stably contain these components
Solution Approach 1:
The patent introduces a specific carrier system as an intermediary to stabilize the antibody and enzyme components. This carrier acts as a mediator that protects the sensitive components from degradation while maintaining their biological activity, thereby resolving the contradiction between achieving stable containment and maintaining preventive effectiveness.
Solution Approach 2:
The patent modifies physical or chemical parameters of the composition (such as pH, ionic strength, or additive composition) to create optimal conditions for stabilizing the antibody and enzyme. By adjusting these parameters, the composition achieves both stable containment and sustained preventive action against odontonecrosis and periodontal disease.
2Duration of action of stationary object
If the antibody and enzyme are included to prevent plaque adhesion, then the disease prevention is improved, but the components cannot be contained stably over time
Solution Approach 1:
The patent incorporates stabilizing agents and carriers that are pre-prepared to protect the antibody and enzyme from degradation. These components are included in advance in specific concentrations and formulations that ensure long-term stability, allowing the composition to maintain preventive action over extended periods without component degradation.
Solution Approach 2:
The patent creates a composite formulation combining the antibody, enzyme, stabilizing agents, and carriers in specific ratios. This composite structure provides mutual protection where the stabilizing agents and carriers protect the sensitive biological components, enabling long-term stability and sustained disease prevention activity.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
The composition effectively stabilizes the antibodies and enzymes, preventing plaque formation and reducing the occurrence of odontonecrosis and periodontal diseases by inhibiting bacterial adhesion and enzyme activity.
Implementation Method 1
a metal salt of citric acid
Implementation Method 2
an antibody obtained from a hen egg yolk
Implementation Method 3
at least one selected from the group consisting of lipase, protease
Data Source
AI summary
A stomatological composition is provided. The stomatological composition is capable of stably compounding an antibody obtained from a hen egg yolk, and preventing diseases in an oral cavity such as odontonecrosis and periodontal disease from occurring, or improving such diseases in the oral cavity. The stomatological composition includes at least one selected from the group consisting of lipase, protease and the antibody obtained from the hen egg yolk, citric acid and a metal salt of citric acid. A total amount of the lipase, the protease and the antibody obtained from the hen egg yolk is in the range of 0.001 to 10 wt %. When an amount of the citric acid is defined as “A” [wt %] and an amount of the metal salt of citric acid is defined as “B” [wt %], the following relation is satisfied: 0.005≦A/B≦1. Further, the stomatological composition of the present invention includes a polyglyceryl fatty acid ester or an amino acid-based ampholytic surfactant as a surfactant. Further, the stomatological composition of the present invention includes a collagen.