Streptococcus mitis Composition for Skin Barrier Repair

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Solution Overview

Problem

The skin barrier's functionality is compromised with aging or by external factors, leading to water loss, wrinkles, and skin diseases, with existing solutions lacking effective prevention or treatment.

Innovation Solution

A composition comprising a novel Streptococcus mitis strain, its lysate, or culture product, which strengthens the skin barrier, enhances skin elasticity, and provides anti-aging benefits by increasing collagen expression and improving skin moisture retention.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If the skin barrier is compromised with aging or external factors, then skin protection function deteriorates, but water loss increases and wrinkles form

Engineering Contradiction:
Improveskin barrier functionVSAvoidwater loss
Core Design Contradiction:
ReliabilityVSLoss of substance

Solution Approach 1:

The probiotic Streptococcus mitis and its metabolites enable the skin to self-repair barrier damage by stimulating keratinocytes to produce more ceramides and other lipids, allowing the skin barrier to regenerate and maintain itself without external intervention

Inventive Principle:
Principle #25Self-service

Solution Approach 2:

The probiotic Streptococcus mitis acts as an intermediary organism that mediates between the external environment and skin cells, producing metabolites that signal keratinocytes to repair barrier damage and maintain proper lipid composition

Inventive Principle:
Principle #24Intermediary (Mediator)

2Reliability

If existing skin barrier solutions are used, then some protection is provided, but they lack effective prevention or treatment of skin diseases

Engineering Contradiction:
Improveskin protectionVSAvoiddisease prevention capability
Core Design Contradiction:
ReliabilityVSAdaptability or versatility

Solution Approach 1:

The probiotic Streptococcus mitis and its lysate provide multiple functions simultaneously: barrier repair, anti-inflammatory effects, antimicrobial protection, and moisturization, making a single composition capable of addressing multiple skin concerns that previously required separate treatments

Inventive Principle:
Principle #6Universality (Multi-functionality)

Data Source

PatentUS11752091B2Composition for strengthening skin barrier, moisturizing skin or anti-aging
Publication Date: 2023.09.12 COSMAX INC
  • US11752091B2 patent drawing
  • US11752091B2 patent drawing
  • US11752091B2 patent drawing

AI summary

Provided is a composition comprising a novel strain, a lysate thereof or a culture product thereof, which can demonstrate excellent effects in strengthening skin barrier, moisturizing skin, enhancing skin elasticity or anti-aging, and can be used for a cosmetic composition or health functional food.