Subsurface Tissue Imaging for Early Pain Onset Detection

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Solution Overview

Problem

Current methods for detecting early pain onset are subjective and rely on surface measurements, which are delayed and non-linear due to sweat reabsorption, making them ineffective for timely and accurate pain assessment.

Innovation Solution

The method involves analyzing representations of subsurface tissue, such as microwave or thermal images, to detect pain features indicative of pain onset, allowing for quicker and more sensitive detection of pain before it reaches the skin surface.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Measurement precision

If surface tissue measurement is used to detect pain onset, then the measurement can be performed at the skin surface, but the detection is delayed due to sweat reabsorption and non-linear response

Engineering Contradiction:
Improvepain detection accuracyVSAvoiddetection latency
Core Design Contradiction:
Measurement precisionVSLoss of time

Solution Approach 1:

Instead of measuring sweat at the skin surface (conventional approach), the patent inverts the measurement location to subsurface tissue. By using imaging techniques to detect sweat gland activity beneath the skin surface, the system captures pain-related physiological changes before sweat reaches the surface and undergoes reabsorption, thereby eliminating detection latency and non-linear response issues.

Inventive Principle:
Principle #13The other way round (Inversion)

2Reliability

If electrodes are used for electrodermal activity measurement, then objective pain measurement can be achieved, but the device complexity increases and requires direct skin contact

Engineering Contradiction:
Improveobjective measurement capabilityVSAvoidelectrode requirement
Core Design Contradiction:
ReliabilityVSDevice complexity

Solution Approach 1:

The patent replaces the mechanical/electrical electrode-based measurement system with an optical/imaging-based system. Instead of using electrodes to measure electrodermal activity, the invention uses imaging techniques (such as optical coherence tomography or other subsurface imaging methods) to visually detect and measure sweat gland activity and subsurface tissue changes, thereby eliminating the need for electrodes and direct skin contact while maintaining objective measurement capability.

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

3Ease of manufacture

If self-report questionnaires are used for pain assessment, then the measurement method is simple, but the measurement is subjective and cannot be performed continuously

Engineering Contradiction:
Improvemeasurement method simplicityVSAvoidmeasurement objectivity
Core Design Contradiction:
Ease of manufactureVSReliability

Solution Approach 1:

The patent enables the tissue to 'self-report' its physiological state through naturally occurring sweat gland activity and subsurface tissue changes that occur in response to pain. By imaging these self-generated physiological markers, the system obtains objective pain measurement data without requiring the subject to actively report or interact with the measurement device, thereby combining simplicity with objectivity.

Inventive Principle:
Principle #25Self-service

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

This approach enables rapid detection of pain onset, potentially before the subject feels pain, and eliminates the need for electrodes, providing a more reliable and efficient method for pain assessment.

Implementation Method 1

analysing a representation of subsurface tissue of the subject

Methodology Applied
Scientific EffectMicrowave radiation: Microwave Radiation

Implementation Method 2

analysing a representation of subsurface tissue of the subject, such as microwave or thermal images

Methodology Applied
Scientific EffectThermal radiation: Thermal Radiation

Data Source

PatentEP4537739A1Onset of pain
Publication Date: 2025.04.16 KONINKLIJKE PHILIPS NV
  • EP4537739A1 patent drawingFigure 1~2
  • EP4537739A1 patent drawingFigure 3A~3B
  • EP4537739A1 patent drawingFigure 4

AI summary

Proposed concepts thus aim to provide schemes, solutions, concept, designs, methods and systems pertaining to indicating onset of pain in a subject. In particular, embodiments aim to provide a method for indicating onset of pain in a subject. This can be achieved by analysing a representation of subsurface tissue of the subject to detect one or more pain features indicative of onset of pain in the subject. From the one or more pain features, an indication of (past, present, or future) pain onset in the subject can be determined.