Succinoglucan O/W Emulsion Stability Against Phase Inversion
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Solution Overview
Problem
Existing oil-in-water (O/W) emulsions with hydrophilic emulsifiers face instability due to phase inversion during manufacturing and storage, particularly when using medium-polar to polar lipids, leading to undesirable phase separation.
Innovation Solution
Incorporation of succinoglucan, a partially esterified polysaccharide, in combination with specific emulsifiers and emulsion preparation methods, stabilizes the O/W emulsion by reducing phase inversion tendencies.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Stability of the object's composition
If water-soluble polymers are used as film-forming agents, then film formation is achieved, but the emulsion becomes unstable and shows signs of bacterial contamination
Solution Approach 1:
The patent changes the chemical nature of the film-forming agent from water-soluble polymers to water-insoluble or water-swellable polymers. This parameter change in solubility fundamentally alters the system's stability profile, eliminating bacterial contamination while maintaining film formation capability through a different mechanism (water-swellable polymer forming flexible films upon water absorption).
Solution Approach 2:
The patent replaces expensive, unstable water-soluble polymer systems with more stable, cost-effective water-insoluble polymer alternatives. The water-insoluble polymers provide long-term stability without requiring complex preservation systems, effectively replacing short-lived unstable formulations with durable stable ones.
2Ease of operation
If conventional emulsifiers are used, then emulsion formation is achieved, but the cosmetic effect is insufficient and skin feels dry and tight
Solution Approach 1:
The patent employs a composite approach by combining water-swellable polymers with specific emulsifiers (polyglyceryl-3 distearate and/or polyglyceryl-3 oleate) in defined ratios. This composite formulation creates synergistic effects where the emulsifier stabilizes the oil-in-water emulsion while the water-swellable polymer provides cosmetic benefits and moisture retention, eliminating the dry and tight feeling.
Solution Approach 2:
The patent assigns specific functional roles to different components: the emulsifier handles emulsion stabilization while the water-swellable polymer specifically addresses cosmetic feel and moisture retention. This functional differentiation allows each component to optimize its local role, providing superior cosmetic effects without compromising skin comfort.
3Duration of action of moving object
If water-soluble polymers are used for film formation, then film properties are achieved, but the polymers are quickly metabolized and provide only temporary effect
Solution Approach 1:
The patent fundamentally changes the solubility parameter of the film-forming polymer from water-soluble to water-insoluble or water-swellable. This parameter change transforms the polymer's interaction with the environment, making it resistant to metabolization and degradation, thereby providing long-lasting film formation effects rather than temporary ones.
4Ease of operation
If the emulsion has high water content for cosmetic benefits, then skin hydration is improved, but the emulsion stability deteriorates
Solution Approach 1:
The patent introduces water-swellable polymers as intermediary substances that can accommodate high water content while maintaining stability. These polymers absorb and bind water molecules, acting as a buffer that prevents water from disrupting the emulsion structure, thus allowing high water content for skin hydration without compromising stability.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
The emulsion remains stable over various temperature and storage conditions, maintaining consistency as an ointment, cream, or thin lotion, and can be used as a spray or impregnating medium for plasters or cloths, enhancing skin care benefits.
Implementation Method 1
the polymer is capable of forming a flexible film on the skin and has the ability to swell upon contact with water
Implementation Method 2
Cosmetic o/w emulsion containing succinoglucan
Data Source
AI summary
The invention relates to cosmetic oil-in-water emulsions (O/W emulsions) containing, in addition to a water phase, one or more oil phases dispersed therein and a) one or more anionic emulsifiers and/or b) one or more non-ionic emulsifiers and c) one or more succinoglucans.