Suction Actuated Valve Mechanical Advantage

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Solution Overview

Problem

Existing dry powder inhalers face challenges in efficiently aerosolizing medicaments using user inhalation alone, as auxiliary energy is often required to ensure effective delivery of medicaments deep into the lungs, and existing mechanisms lack efficient actuation methods to manage compressed air for aerosolization.

Innovation Solution

A suction actuated valve system with a compressed air lumen, control chamber, and trigger assembly that provides mechanical advantage through a displaceable membrane, allowing relatively weak suction to actuate the valve and control the compressed air flow for aerosolization, coupled with a biasing mechanism to ensure precise delivery of compressed air to the drug feeder.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Productivity

If a suction actuated valve mechanism is used to control compressed air flow for aerosolization, then aerosolization efficiency is improved, but device complexity increases

Engineering Contradiction:
Improveaerosolization efficiencyVSAvoidvalve mechanism complexity
Core Design Contradiction:
ProductivityVSDevice complexity

Solution Approach 1:

The valve mechanism is segmented into distinct functional components: a control chamber for suction input, a displaceable membrane for force amplification, a trigger assembly for valve actuation, and a compressed air lumen for medicament delivery. This segmentation allows each component to perform its specific function efficiently while simplifying the overall design and manufacturing process.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The displaceable membrane acts as an intermediary between the user's weak suction force and the trigger assembly. It provides mechanical advantage by having a larger cross-sectional area than the trigger, amplifying the suction force to reliably actuate the valve and control compressed air flow for effective aerosolization.

Inventive Principle:
Principle #24Intermediary (Mediator)

2Force

If mechanical advantage is provided through displaceable membrane area difference, then actuation force requirement is reduced, but manufacturing precision requirements increase

Engineering Contradiction:
Improveactuation forceVSAvoidmembrane area ratio precision
Core Design Contradiction:
ForceVSManufacturing precision

Solution Approach 1:

The design changes the physical parameters of the membrane, specifically its cross-sectional area, to provide mechanical advantage. By making the membrane's cross-sectional area larger than the trigger's cross-sectional area, the system reduces the suction force needed for actuation while maintaining reliable valve control.

Inventive Principle:
Principle #35Parameter changes

3Productivity

If compressed air is used to aerosolize dry powder medicament, then delivery depth into lungs is improved, but energy management complexity increases

Engineering Contradiction:
Improvemedicament delivery depthVSAvoidcompressed air energy management
Core Design Contradiction:
ProductivityVSUse of energy by moving object

Solution Approach 1:

The control chamber provides feedback control for the compressed air release mechanism. When the user inhales and creates suction, this negative pressure is transmitted to the control chamber, which automatically triggers the valve to open and release the pre-loaded compressed air. The system responds to the user's inhalation action by automatically delivering the appropriate amount of compressed air for effective aerosolization and deep lung delivery.

Inventive Principle:
Principle #23Feedback

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

Enables efficient aerosolization and deeper lung delivery of dry powder medicaments by utilizing the mechanical advantage of the suction actuated valve to manage compressed air flow, ensuring effective aerosolization and improved drug distribution in the lungs.

Implementation Method 1

the trigger may have a first cross-sectional area and the displaceable membrane may have a second cross-sectional area greater than the first cross-sectional area such that when suction is provided by the control chamber the displaceable membrane may provide a mechanical advantage for moving the trigger from the closed configuration to the open configuration

Methodology Applied
Scientific EffectMechanical Advantage: Mechanical Advantage

Implementation Method 2

the compressed air lumen may comprise an elastic tube and in the closed configuration, the trigger assembly is configured to compress the elastic tube to occlude the compressed air lumen and in the open configuration the trigger assembly is configured to decompress the elastic tube to open the compressed air lumen

Methodology Applied
Scientific EffectElasticity: Elasticity

Data Source

PatentEP3319673B1Dry powder inhaler apparatus
Publication Date: 2019.10.23 LI JIANHE
  • EP3319673B1 patent drawingFigure 1~2
  • EP3319673B1 patent drawingFigure 3~4
  • EP3319673B1 patent drawingFigure 5~6

AI summary

A suction actuated valve, for a dry powder inhaler, comprising: a compressed air lumen; a control chamber for providing suction; and a trigger assembly, in fluid communication with the control chamber, comprising: a displaceable membrane contained within the control chamber and displaceable within the control chamber, the displaceable membrane configured to seal the control chamber such that suction provided by the control chamber displaces at least a portion of the displaceable membrane to provide an opening force to the trigger assembly for moving the trigger assembly from a closed configuration to an open configuration; and a trigger coupled to the displaceable membrane, the trigger configured, in the closed configuration, to occlude the compressed air lumen and configured, in the open configuration, to open the compressed air lumen; wherein the trigger has a first cross-sectional area and the displaceable membrane has a second cross-sectional area greater than the first cross- sectional area such that when suction is provided by the control chamber the displaceable membrane provides a mechanical advantage for moving the trigger from the closed configuration to the open configuration.